| Sequence 1: | NP_610995.1 | Gene: | SMC2 / 36653 | FlyBaseID: | FBgn0027783 | Length: | 1179 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006297.2 | Gene: | SMC1A / 8243 | HGNCID: | 11111 | Length: | 1233 | Species: | Homo sapiens |
| Alignment Length: | 1302 | Identity: | 298/1302 - (22%) |
|---|---|---|---|
| Similarity: | 582/1302 - (44%) | Gaps: | 211/1302 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 YVKKLVLDGFKSYGRRTEIEGFDPEFTAITGLNGSGKSNILDSICFVLGISNLQNVRASALQDLV 66
Fly 67 Y--KNGQAGITKATVTIVFDNTNPAQCPQGYEKCREISVTRQVVVGGKNKFLINGKLVQNKKVQD 129
Fly 130 FFCSIQLNVNNPNFLIMQGKIQQVLNMKPKEVLSMVEEAAGTSQYKTKRDATKTLIEKKETKV-- 192
Fly 193 ---RETKVLLDEEVLPKLVKLRQERSAYQEYQKICRDIDFLIRIHISAKYLKQCETLKTVEANEH 254
Fly 255 KIEDRIANCKATHAKNLAEVESIENSVKEM----------QQQIDAEMGGSIKNLETQLSAKRAL 309
Fly 310 EATATGSLKAAQGTIQQDEKKIRMASKNIEDDERALAKKEADMAKVQGEFESLKEADARDSKAYE 374
Fly 375 DAQKKLEAVSQG----LSTNEN-------------GEASTLQEQLIVAKEQFSEAQTT----IKT 418
Fly 419 SEIELRHTRGVLKQREGETQTNDAAYVKDKKLHDQLVVEIKNLERQLQSLDYEGGHFEKLKQRRN 483
Fly 484 DLHMRKRDLKRELDRCNASRYDLQYQDPEPNFDRRK--------------VRGLVGKLFQVKDMQ 534
Fly 535 NSMALVQTAGGSLYSYVTDDDVTSKKIL-----QRGNLQRRVTLIPINKIQSGSLNRNVVEYAQN 594
Fly 595 KVGAENVQWAMSLIDYDRYYEP----VMKFCFGGTLICKDLIVAKQISYDPRINCRSVTLEGDVV 655
Fly 656 DPHGTVSGGAAPKGANVLE-ELHAIKQIEKEYREIDSEIAQ------VEKQIASIENQALAFNKM 713
Fly 714 KENLDLRQHELTMCENRLAQTTFQQN---QAEIEEMRERVKTLEQQIIDSREKQ-KTSQAKIVDI 774
Fly 775 EAKLAD-------AKGYRERELNAATNEIKVTKQRAEKSRANWKKR---EQEFETLQLE------ 823
Fly 824 ------ITELQKSIETAKKQHQEMIDNLEKFKAELDALKVNSSSAASEVTELEQAIKEQKDKLRD 882
Fly 883 QNKEM--------------------RNQLVKKEKMLKENQEIELEVKK------KENEQKKISSD 921
Fly 922 AKEAKKRMEALEAKYPWIPEEKN--CFGMKNTRYDYSKEDPHEAGNKLAKMQEKKDKMERTL--N 982
Fly 983 MNAIMVLDREEENFKETERRRNIVAMDKEKIKKIIVKMDEEEQDQLNKAATEVNTNFSGIFSSLL 1047
Fly 1048 --PGAEAKLNPVH-TNGCLTGLEIKVGFNGIWKESLGELSGGQKSLVALSLVLAMLKFSPAPLYI 1109
Fly 1110 LDEVDAALDMSHTQNIGSMLKQHFT-NSQFLIVSLKDGLFNHANVLFRTLFEEGVSTITRQVSRQ 1173
Fly 1174 AT 1175 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SMC2 | NP_610995.1 | Smc | 1..1168 | CDD:224117 | 297/1293 (23%) |
| ABC_SMC2_euk | 1..>170 | CDD:213240 | 56/169 (33%) | ||
| SMC_hinge | 520..637 | CDD:214944 | 25/125 (20%) | ||
| V_Alix_like | 690..933 | CDD:187408 | 62/300 (21%) | ||
| P-loop_NTPase | <1073..1167 | CDD:304359 | 32/94 (34%) | ||
| SMC1A | NP_006297.2 | SMC_N | 3..1210 | CDD:308206 | 296/1289 (23%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 284..308 | 8/30 (27%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 348..369 | 4/20 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 947..966 | 2/18 (11%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1196 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||