DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SMC2 and AgaP_AGAP011346

DIOPT Version :9

Sequence 1:	NP_610995.1	Gene:	SMC2 / 36653	FlyBaseID:	FBgn0027783	Length:	1179	Species:	Drosophila melanogaster
Sequence 2:	XP_309304.3	Gene:	AgaP_AGAP011346 / 1270581	VectorBaseID:	AGAP011346	Length:	228	Species:	Anopheles gambiae

Alignment Length:	165	Identity:	35/165 - (21%)
Similarity:	66/165 - (40%)	Gaps:	51/165 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   314 TGSLKAAQGTIQ-QDEKKI-RMASKNIEDDERALAKKEADMAKVQGEFESLKEADARDSKAYEDA 376
            ||.:..||..:. ||..|: |:|.:|      .|.:.||.:...:|..:.|     ..|||...|
Mosquito    58 TGLVSVAQEPLSLQDRNKLKRLAQEN------RLYRLEAHVTDSEGVTKFL-----TSSKACALA 111

  Fly   377 QKKL--------------EAVSQGLSTNENGEASTLQEQLIVAKEQFSEAQTTIKTSEIELRHT- 426
            :.:|              .||:|.::.....|.:.|....:...::|:        :::.::||
Mosquito   112 KSQLTDVLWVSLDHTGTVTAVTQSVNNGNLNECADLSNSDVDVLDEFN--------TDVYVKHTE 168

  Fly   427 -----------RGVLKQRE----GETQTNDAAYVK 446
                       :.:.::||    |||:.|.:.:.|
Mosquito   169 PAPIPDTASFIQKMEREREARERGETKDNRSFFAK 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SMC2	NP_610995.1	Smc	1..1168	CDD:224117	35/165 (21%)
		ABC_SMC2_euk	1..>170	CDD:213240
		SMC_hinge	520..637	CDD:214944
		V_Alix_like	690..933	CDD:187408
		P-loop_NTPase	<1073..1167	CDD:304359
AgaP_AGAP011346	XP_309304.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1196
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900