Protein Alignment CG10209 and NAIF1

DIOPT Version :10

• Sequence 1: NP_001260982.1
• Gene: CG10209 / 36652
• FlyBaseID: FBgn0033971
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_931045.1
• Gene: NAIF1 / 203245
• HGNCID: 25446
• Length: 327
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 70/453 - (15%)
• Similarity: 135/453 - (29%)
• Gaps: 186/453 - (41%)

  Fly    32 WEKIQAALNTIGP-KKTIIQWKKCWRDMRLTTRKKLAELKRCQLSGGSPPPGIELNQEDNDIIDI 95
            |..|...:|.:.. ::.:.:.||.|.|::...|:|:|:::.....|.:|.|    .:||.
Human    48 WHGILRRVNAVATCRRELPEVKKKWSDLKTEVRRKVAQVRAAVEGGEAPGP----TEEDG----- 103

  Fly    96 VGTEYFYEEMNGELKAENFLTGLDYAPEHLCDAILTAAVGHHQHNMQHQKDPQSHAGQQQQQDHH 160
                                                                             
Human   104 ----------------------------------------------------------------- 103

  Fly   161 TNDGETNDAPGSSNGGSYQGHPVSQLQAHNGSGGGGEHSGGGQSHSGMLQHPAFHGGLHPHLLRR 225
                    |.|...||              ||||||               ||    :.|.||
Human   104 --------AGGPGTGG--------------GSGGGG---------------PA----VAPVLL-- 125

  Fly   226 QHGSGSLSRESPFEEKLLQFMQDAFPKKSKKRKNRDPDKLFLLSLYEEIKRVPEEIRLDVKSELM 290
                      :|.::::...:.:|                .::||       |....:
Human   126 ----------TPMQQRICNLLGEA----------------TIISL-------PSTTEI------- 150

  Fly   291 QILKKYQKKSPVKAEKPAPSSTSTSSKLSSSSSGSSTVTTHLSHSMYQLQKKYEKGEREP--SPQ 353
                     .||..   .||:|:.::.::.:.  ..|.||:  |::.:...:|...|..|  .|:
Human   151 ---------HPVAL---GPSATAAAATVTLTQ--IPTETTY--HTLEEGVVEYCTAEAPPPLPPE 199

  Fly   354 SQVERVASAGAVAVPIHTSQQLPLFQLQKKYEENSVEKVH----QQQQQQQSEQRKHVEAAQALH 414
            :.|:.:|.....:|.....:........|..:|..|..:|    .|..:||::..:.:..:|.:.
Human   200 TPVDMMAQHADTSVKPQALKSRIALNSAKLIQEQRVTNLHVKEIAQHLEQQNDLLQMIRRSQEVQ 264

  Fly   415 AAHQQPPPPPPNEHLHHPQMAHNIMFPLGQLRNEQPTAQQHQHGHNPHQQQQQHPHQQQQQGQ 477
            |..|:...    :.:...|.|.:::..:  ||......:::...:..:......|.|..|.||
Human   265 ACAQERQA----QAMEGTQAALSVLIQV--LRPMIKDFRRYLQSNTANPAPASDPGQVAQNGQ 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10209	NP_001260982.1	GT1	3..68	CDD:474047	9/36 (25%)
		BESS	261..295	CDD:460758	3/33 (9%)
NAIF1	NP_931045.1	Required for nuclear localization and apoptosis-inducing activity	1..70		3/21 (14%)
		Myb_DNA-bind_5	8..85	CDD:433544	9/36 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..118		15/141 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..327		5/19 (26%)