DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and SOA1

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_012100.1	Gene:	SOA1 / 854640	SGDID:	S000001428	Length:	542	Species:	Saccharomyces cerevisiae

Alignment Length:	511	Identity:	105/511 - (20%)
Similarity:	169/511 - (33%)	Gaps:	191/511 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QVEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAAL---AE----- 59
            :::.:..||  .||.|....:||.|:...:.|.......:.:|:.:...|....:   :|
Yeast    76 KMDLKIFLW--VFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLASELPGNL 138

  Fly    60 MNERFSLER----WFLDWANIPYEKNGFHWNEKQ-------QGALLGSFFWAHWTLQIPGGILAT 113
            :::||..||    ..:.|:.|...:.|.. |..|       .|.:.|.|        ||..||..
Yeast   139 LSKRFGPERVIPVQIVLWSVICITQAGLK-NRGQFIATRCLLGMVQGGF--------IPDNILYL 194

  Fly   114 KY---GTKLVFGWSNGIGVFCCF--LIPIVSYWSYTGLIILRVFQGWITGLA-WPSMHVLTAKWI 172
            .|   |.:|.|    .:..|.|.  |..|:.....:|:|.:|    .|..|| |..:.:
Yeast   195 SYYYTGAELTF----RLSFFWCAIPLFQILGSLLASGIIEMR----GIHNLAGWQYLFI------ 245

  Fly   173 PPNERSKFVSAYLGSSVGVALFYPIFGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHP 237
                    :..:|..|||||.||                                |:...|.:..
Yeast   246 --------IEGFLSLSVGVASFY--------------------------------LMRRGPTQTG 270

  Fly   238 RIADSERK-----FIEKSLGASI---QGSKGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHA 294
            ..|..:.|     :.||.:...|   ..|||.     ::..:||....:        |:||
Yeast   271 ESAFHKGKSLFTEYEEKIMVNRILRDDPSKGD-----MSNRQPVTFKEI--------LYTL---- 318

  Fly   295 PTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKG- 358
             |.|.|   |.:    |:.|                                 :..||...|.|
Yeast   319 -TEFDL---WPL----FIQG---------------------------------ITAFISLQTVGS 342

  Fly   359 ---LIVLALAY--FGYNATA----AIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMI 414
               ||:.:|.|  |..|..|    |::|:.:           |||:::........:.:|::.:
Yeast   343 YLSLILKSLNYSTFLSNILAIPGQALLLINL-----------PLAALLSRKLKEKSLCVGIANV- 395

  Fly   415 GGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFSESKLQPWNS 470
                 ::.||||..:.....| :.|....|||       |||.:.::.|.|..|.|
Yeast   396 -----WVLPFIVSLVALPTDT-NPWIKYILLT-------GILGLPYTHSILAGWVS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	105/511 (21%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	84/414 (20%)
SOA1	NP_012100.1	MFS_FEN2_like	76..496	CDD:340885	105/511 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050