DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and slc17a5

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	468	Identity:	157/468 - (33%)
Similarity:	251/468 - (53%)	Gaps:	25/468 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTD-LAALAEMNERFSLERW 69
            ||..|..|..:||.:.|.:|:||::.:|||:........|.|.....| .:|.|.::
Frog    39 ARYNLALMALLGFFMLYALRVNLSVALVDMVNSTSTPRENTTANICPDHTSAPAVLH-------- 95

  Fly    70 FLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWS-NGIGVFCCF 133
                 |...:|  :.|:...||.:|||||:.:...|||||.:|.|.|.|.:.|:. .|..|| ..
Frog    96 -----NSTGQK--YDWDANTQGWILGSFFYGYILTQIPGGYVAGKIGGKQLLGFGILGTAVF-TL 152

  Fly   134 LIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGVALFYPI 197
            |.|:.:.:....||.:|..:|...|:.:|:||.:.|:|.||.|||:.:| :|.|:.:|..:..|:
Frog   153 LTPLAADFGAGCLIAVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLSLSYAGAQLGTVVSLPV 217

  Fly   198 FGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKGPT 262
            .|.|..:..|.:|:||.|.:|.||||.|.|||.|:|..|..|.|||:::|..:|...:...|. .
Frog   218 SGLICYYMDWIYVFYIFGTLGVLWFIMWCFLVSDTPQSHRSITDSEKEYILYTLQNQLSYRKS-V 281

  Fly   263 PWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVF 327
            |..|:..|.|:|..:||.:...|..:||:|..|||.:.|..:|.:..||||.||:|...:|..:.
Frog   282 PCCAMMKSLPLWAIIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQENGFLSALPYLGCWVFMIMA 346

  Fly   328 SIFADYLLRTDKMSRTNVRKLATFICCGTKG--LIVLALAYFGYNATAAIVLVTVATMLHGAVSS 390
            .:.||.|.....:|...|||:  |...|..|  :.:||..|.|.|.:.|:|.:|::|.|.|...:
Frog   347 GVIADCLREKLNISTKVVRKI--FNTLGMLGPAIFLLAAGYTGCNYSLAVVFLTLSTTLGGFSVA 409

  Fly   391 GPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGI 455
            |...:.:|::|::||::||::.....:||.:.|.|...|||:| |::.|:.||.:.:.:.....|
Frog   410 GYGINHLDIAPSFAGLLLGITNTFATIPGMVGPVIAKALTHDN-TVEQWQIVFYIAAAINFFGAI 473

  Fly   456 LYVLFSESKLQPW 468
            .:::|:...:|.|
Frog   474 FFIIFASGNVQDW 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	157/468 (34%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	135/387 (35%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	151/442 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000