DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and SLC17A1

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_016866688.1	Gene:	SLC17A1 / 6568	HGNCID:	10929	Length:	517	Species:	Homo sapiens

Alignment Length:	469	Identity:	124/469 - (26%)
Similarity:	211/469 - (44%)	Gaps:	45/469 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MTFIGFIVNYMI---RINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFLDWA 74
            ::|:....|.:|   |..||:|:|.|:             ||||...|...:.:..|:
Human    72 LSFLVHCCNVIITAQRACLNLTMVVMV-------------NSTDPHGLPNTSTKKLLD------- 116

  Fly    75 NIPYEKNG-FHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIPIV 138
            ||   ||. ::|:...||.:|.|..:....:|:|.|..:..|.||.:.|::..:......|||..
Human   117 NI---KNPMYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSVLSLLIPPA 178

  Fly   139 SYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGVALFYPIFGYII 202
            :......:::.|..||...|:...:...:..||.||.||.:..| :..|..:|..:...:.|.|.
Human   179 AGIGVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLLVTGVIC 243

  Fly   203 DWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKGPTPWKAI 267
            :...|..|:||.|..|....:.|..|.:|.|.:||.|:.||:::|..||...:..|:...|.|||
Human   244 ESLGWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSLVQQVSSSRQSLPIKAI 308

  Fly   268 ATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFAD 332
            ..|.|||......:...|....:..:.|.:...:.|.||:..||||.||:|...:...:....:|
Human   309 LKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPYLFAWICGNLAGQLSD 373

  Fly   333 YLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGY---NATAAIVLVTVATMLHGAVSS---- 390
            :.|..:.:|...||||.|     ..|.::.|:  ||.   ..::....:.:..:|.||..|
Human   374 FFLTRNILSVIAVRKLFT-----AAGFLLPAI--FGVCLPYLSSTFYSIVIFLILAGATGSFCLG 431

  Fly   391 GPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAW-KNVFLLTSLMLTGSG 454
            |...:.:|::|.|.|.:...|.:.|.:.|.|:..:.|.:...:.. .|| |...|:.::.:||.
Human   432 GVFINGLDIAPRYFGFIKACSTLTGMIGGLIASTLTGLILKQDPE-SAWFKTFILMAAINVTGL- 494

  Fly   455 ILYVLFSESKLQPW 468
            |.|::.:.:::|.|
Human   495 IFYLIVATAEIQDW 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	124/469 (26%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	106/393 (27%)
SLC17A1	XP_016866688.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810