Protein Alignment NaPi-T and SLC17A7

DIOPT Version :9

• Sequence 1: NP_001260981.1
• Gene: NaPi-T / 36651
• FlyBaseID: FBgn0016684
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 158/507 - (31%)
• Similarity: 256/507 - (50%)
• Gaps: 53/507 - (10%)

  Fly     7 RTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFL 71
            |.::..|:.:||.:::.||.||.:.||.|      :.::.||..
Human    62 RYIIAIMSGLGFCISFGIRCNLGVAIVSM------VNNSTTHRG--------------------- 99

  Fly    72 DWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIP 136
              .::..:|..|.|:.:..|.:.|||||.:...|||||.:..|:....|||::.........|||
Human   100 --GHVVVQKAQFSWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIP 162

  Fly   137 IVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVGVALFYPIFGY 200
            ..:...|..:|.:|:.||.:.|:.:|:.|.:.:||.||.|||:. .:|:.||..|..:..|:.|.
Human   163 SAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGV 227

  Fly   201 IIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQ----GSKGP 261
            ::.::.|..|:|:.|..|..|::.|..:.::|||.||.|::.|||:||.::|.|.:    .:|..
Human   228 LVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPLTKFS 292

  Fly   262 TPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYV 326
            |||:...||.||:..:||.:...|..:.|:...|.||..:..:.|...|.:|.||||:..:...:
Human   293 TPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPI 357

  Fly   327 FSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNAT--AAIVLVTVATMLHGAVS 389
            ....||:|.....||.||||||..   ||..|:....|...||:.:  .||..:.:|....|...
Human   358 GGQIADFLRSRRIMSTTNVRKLMN---CGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAI 419

  Fly   390 SGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSG 454
            ||...:.:|::|.||.|::|:|..:|.:.|.:.|.|||.:| .::|.:.|:.|||:.||:..|..
Human   420 SGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMT-KHKTREEWQYVFLIASLVHYGGV 483

  Fly   455 ILYVLFSESKLQPWNSGCHQLPDSGLKELQN-LGRDQ----DD---EEEKKP 498
            |.|.:|:..:.|||..     |:...:|... :|.||    ||   |:|.:|
Human   484 IFYGVFASGEKQPWAE-----PEEMSEEKCGFVGHDQLAGSDDSEMEDEAEP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	148/473 (31%)
		MFS	76..460	CDD:119392	131/390 (34%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	143/456 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		11/39 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820