DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and CG30265

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	132/519 - (25%)
Similarity:	228/519 - (43%)	Gaps:	60/519 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGQVEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFS 65
            :|....:|:|   .|......|:.|:|:.:.:|.|           |:..||:
  Fly    11 LGMRHVQTLL---LFFNITCLYIGRLNVGVAVVAM-----------TNAESTN------------ 49

  Fly    66 LERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGW-SNGIGV 129
                    .:.|    .:.|...|:..:|.||||.:...|..||.|..:||.|.|..| |...|:
  Fly    50 --------PDFP----EYDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGI 102

  Fly   130 FCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVG--V 191
            |.......:.:..:.....:||..|:..||.:|.:|...|:|.||.||::. ..::.|...|  .
  Fly   103 FSALTPLFIGFGEWQAYCGIRVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVC 167

  Fly   192 ALFYPIFGYII-DWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASI 255
            |:|:.  |.|. ....|..:.|:...:...|...|.....|:..|...|...|..:||.||..:.
  Fly   168 AMFFS--GMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNE 230

  Fly   256 QGSKG--PTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHL 318
            ...|.  |.||.||.||.|.:..:||:....|||.||....|||...:...::::..|.|.||.|
  Fly   231 DYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFL 295

  Fly   319 MRMLFAYVFSIFADYLLRTDKMSRTNVRK----LATFICCGTKGLIVLALAYFGY-NATAAIVLV 378
            ...:.:||:.|.||.||..:::|.|.:||    ||.:|.|.|    ::.:.:... ....||.|:
  Fly   296 AMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCAT----LIGIGFLDQEQKNLAIALM 356

  Fly   379 TVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVF 443
            |::..::...:.|...:.:|||||:|.|::|:......:...::|..||.:.|.::..:.|:.||
  Fly   357 TISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVF 421

  Fly   444 LLTSLMLTGSGILYVLFSESKLQPWNSG---CHQLPDSGL-KELQNLGRDQDDEEEKKPLKSDH 503
            ::.:::......:::.:..:..|||::.   ..::||..: ..:...|:..|...:|..:...|
  Fly   422 IIAAVIFFIGNCVFLYYGTAVSQPWDAEDYLTEKVPDLAIAPAIHEAGKGIDGPSQKSMILKFH 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	126/487 (26%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	111/395 (28%)
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	125/479 (26%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	122/463 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970