DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and CG15096

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	480	Identity:	142/480 - (29%)
Similarity:	225/480 - (46%)	Gaps:	71/480 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFLDWANIP 77
            :.|....|.|..|:||::.:|.|                ||.|:   :|..|.
  Fly    42 LLFFALTVAYGCRVNLSVAVVAM----------------TDAAS---VNPDFP------------ 75

  Fly    78 YEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCC---FLIPI-- 137
                .::|:||.:..||.||||.:...|:|.|.||.|||.|::.  .:|:.: |.   .|.||
  Fly    76 ----EYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMI--LSGLAI-CSILNILTPICA 133

  Fly   138 -VSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVGVALFYPIFGY 200
             :..|..  :..|||.:|...|:.:||.|.:.::|.||.||:.. ..||.|:..|..|.....|.
  Fly   134 KIGGWQL--VCALRVVEGLCQGVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGV 196

  Fly   201 I----IDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKG- 260
            |    |.|..   ::||.|.:|.:|.:.:.|....||.|...|:..|:|.||.|....:.|.:.
  Fly   197 IAASPIGWPS---IFYISGGIGCVWSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQ 258

  Fly   261 -----PTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMR 320
                 ||||.:..||....:.:|:.....||.:||:|..|:|.:.|...:|::...||.||::..
  Fly   259 PKEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCM 323

  Fly   321 MLFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIV--LALAYFGY----NATAAIVLVT 379
            ...::|||..:..|...:.:||:..|||...|     ||.:  :.|...||    .:..|:||:.
  Fly   324 FAMSFVFSSISAQLNNRNCISRSTSRKLFNSI-----GLWIPMVTLVGLGYVNPDQSELAVVLLC 383

  Fly   380 VATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFL 444
            ....::||...|...:.:|||||:|||::|::..:..:...|:|.|||.:..|....:.|:.||.
  Fly   384 FTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFF 448

  Fly   445 LTSLMLTGSGILYVLFSESKLQPWN 469
            :.:........|||:|.::.:||||
  Fly   449 IAAGFYLVGNTLYVIFGKANVQPWN 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	142/480 (30%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	124/406 (31%)
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	142/480 (30%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	137/469 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970