DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and MFS17

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	149/508 - (29%)
Similarity:	259/508 - (50%)	Gaps:	49/508 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QVEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLE 67
            ::.||.||:::::.||:|::|:|.::|..:|.|||          ::|||...:|.:..:..
  Fly    32 KIPARLVLYFLSWSGFLVSFMMRNDMNFALVAMIA----------NDNSTQNQSLIKSQQIL--- 83

  Fly    68 RWFLDWANIPYEKNGFHWNEKQ---QGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGV 129
                          |...::::   :..::.||:|.:...|:.||:....:|||.|||||.....
  Fly    84 --------------GTGTDDQKTIVKSVVISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATA 134

  Fly   130 FCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYLGSSVGVALF 194
            .|.|::|..:...|..:|:||..||:.:||.||:|:.:...|||..|||:|:|::.|.|:|:.|.
  Fly   135 LCSFMMPSAAQLHYIAVIVLRSIQGFASGLTWPAMYAIVGYWIPLTERSRFMSSFQGFSIGIGLT 199

  Fly   195 YPIFGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGS- 258
            ||:.|:|:....|.:::|..|.:|..|.|.|..|.|::|.|||||...|..:||.::...:..|
  Fly   200 YPLCGFILSEWGWPYIFYTTGTLGLGWCILWYLLAFNTPREHPRITKDELNYIELNVKKEVNSSV 264

  Fly   259 KGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLF 323
            |...||..|..|.|.|...:..:|.|:..:..:.:.||:...:..:|....|||||:|.:...:.
  Fly   265 KVKVPWLQIFKSIPAWAIAITTFGRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYIS 329

  Fly   324 AYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVLVTVATMLHGAV 388
            :.:|...||.::....:..|||||:.|.:.....|:::..:.|.. |....:.:..:|.:...|.
  Fly   330 SVLFCYIADKIVFYKVLCLTNVRKVFTALSQIIPGVLIYCIGYID-NVYILLTVWFIAVIFITAS 393

  Fly   389 SSGPLASMVDLSPNY--AGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLT 451
            .:|.:|:::||:|||  :..||.....|.....||||...|.:.....:||.|:.||.:::::..
  Fly   394 YAGAMANIIDLAPNYGHSAAVLAFCQTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISI 458

  Fly   452 GSGILYVLFSESKLQPWNSGCHQLPDSGLKELQNLGRDQDDEEEKKPLKSDHD 504
            .:.:.|.||..:::|.||.|   ||.:            ||.:|.|.|.:..|
  Fly   459 LTYLFYQLFGTAEIQTWNKG---LPVN------------DDSDEGKVLSTAKD 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	141/476 (30%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	117/389 (30%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	139/470 (30%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	131/453 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247790at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970