DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and MFS10

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	152/497 - (30%)
Similarity:	261/497 - (52%)	Gaps:	48/497 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNET---HENS----TDLAALAEMNE 62
            :.|.:..:|.|:||.|.|.:|:||::.||.|:        |:|   |.||    ||...|...:.
  Fly    66 KTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMV--------NQTAIPHSNSSVIDTDTCPLPAPHH 122

  Fly    63 RFSLERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGI 127
            ..|...        |.::..|.|:|..||.:|||||:.:...|:|||.:|..||.|.::|:...|
  Fly   123 NGSDPN--------PQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLI 179

  Fly   128 GVFCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGV 191
            ......:.|:.::|....|:::|:.:|...|:.:|:||.:.|.||||.||:||.: .|.||::|.
  Fly   180 TAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGT 244

  Fly   192 ALFYPIFGYI--IDWT-RWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLG- 252
            .:..|:.|::  :|:. .|...:||.|::|.||||||.:||:|.|::||||::|||::||:||.
  Fly   245 VISMPLAGWLCSLDFLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQV 309

  Fly   253 --------ASIQGSKG------------PTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTY 297
                    |..:..:|            |.||.::.||.|:|..::.|.|..|..:|.:|..|||
  Fly   310 QRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTY 374

  Fly   298 FRLIHHWNIRATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVL 362
            ...|.|::|::...|:.:|:|.........|..||::|....:|..|..||...:......|.::
  Fly   375 MSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLI 439

  Fly   363 ALAYFGYNATAAIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVG 427
            .:.|.|.:......::.......|||.:|...:.:.|||.|||.:.|::.....:.||::|:::|
  Fly   440 GIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIG 504

  Fly   428 QLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFSESKLQPWN 469
            .:.::.:|:..|..||.|.:.:......:|::|:.::.|.|:
  Fly   505 LIINHRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWS 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	152/497 (31%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	127/408 (31%)
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	152/497 (31%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	126/403 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960