DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and Slc17a4

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	469	Identity:	133/469 - (28%)
Similarity:	216/469 - (46%)	Gaps:	34/469 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 MTFIGFIVNYMI---RINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERW--FLD 72
            :.||..:.|:.|   ::||:..|..|:         .|...|:.|.|..|.....|.:.|  .|.
Mouse    36 LAFILHLCNFSIYTQQMNLSFAITAMV---------NTTVASSQLNASTERPPTNSQDVWNETLQ 91

  Fly    73 WANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIPI 137
            .:..|.    :.|..:.||.||.|..:..:...||.|.:|..:|.|.|.|....|.......||:
Mouse    92 ESKAPV----YDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPL 152

  Fly   138 VSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGVALFYPIFGYI 201
            .:......||:|||.||....:.....:.|.|||.||.|||:.:: |..||.:|..|.....|.|
Mouse   153 AADAGVALLIVLRVIQGMAQVMVLTGQYSLWAKWAPPQERSQLITIAASGSMLGTFLVLIAGGLI 217

  Fly   202 IDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFI-------EKSLGASIQGSK 259
            .....|.:::||.|.:|....:.|..||:|.|..||.|:..||::|       :.|||.|:
Mouse   218 CQALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCSLGWSL---- 278

  Fly   260 GPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFA 324
               |.||:..|.|:|..||:.:...|.|.|:|.:.|||...:...|:|.:|.||.||.:...:..
Mouse   279 ---PIKAMVKSLPLWAIVVSYFCEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFMFGCVCI 340

  Fly   325 YVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVLVTVATMLHGAVS 389
            .:..:.||:||....:....:|||.|.:.......|:|.|.:...:.:..:..:.::::......
Mouse   341 ILGGLLADFLLSRKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSVFASLCD 405

  Fly   390 SGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTGSG 454
            ||.|.:.:|::|.|||.:.|:..:...:.|.|:|.:.|.....:... .|:|||.|.:.:.....
Mouse   406 SGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEF-GWRNVFFLAAAIDVVGL 469

  Fly   455 ILYVLFSESKLQPW 468
            :.|::||.:::|.|
Mouse   470 LFYLIFSRAEVQDW 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	133/469 (28%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	113/391 (29%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	133/469 (28%)
		MFS	98..475	CDD:119392	112/384 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810