DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NaPi-T and liz1

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001342731.1	Gene:	liz1 / 2540342	PomBaseID:	SPBC2G2.01c	Length:	514	Species:	Schizosaccharomyces pombe

Alignment Length:	571	Identity:	113/571 - (19%)
Similarity:	192/571 - (33%)	Gaps:	169/571 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGQVEARTVL---WYM---TFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAE 59
            :.:||.:.::   |::   ..:.:.:||:.|.::|                        .|.|:.
pombe    17 LNKVEQKLLIKIDWFILSYCCVSYFINYLDRSSIN------------------------NAYLSG 57

  Fly    60 MNERFSLERWFLDWANIPYEKNGFHWNEKQQ-------GALLGSFFWAHWTLQIPGGILATKYGT 117
            |.|...:                 |.||.|.       |.::|         |:||.....:...
pombe    58 MQEDLKM-----------------HGNELQDINVVFTCGYIIG---------QLPGSYALQRVPA 96

  Fly   118 KLVFGWSNGI-GVFCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFV 181
            :|.|...|.: |:...|...:   .|...|:|||.|........:...|.:...|...:|..|..
pombe    97 RLWFSVMNILWGLMTIFSFAV---HSVRALMILRFFMAVAEASTFAGTHYILGAWYKESELCKRA 158

  Fly   182 SAYLGSSVGVALFYPIFGYII-----------DWTRWEWVYYICGIVGTLWFIAWQFLVFDSP-- 233
            ..:..|.:...:|   .||:.           ..:.|.|::.|.||:.....:...||..|.|
pombe   159 GIFSASGLVGTMF---AGYLQTAVHSSLNGKGGLSGWRWLFIIDGILTIPLSLYGLFLFPDVPET 220

  Fly   234 AEHPRIADSERKFIEKSLGASIQGSKGPTPWKAIATSRPVWLNVVAQWGGIWGL-----FTLMTH 293
            .:.|...:.|::...|.|.|  :..|.|...|||.       ::|..| .|:||     |:..|.
pombe   221 TKAPYFTEQEKELSFKRLPA--RPKKKPLTLKAIK-------DIVRSW-RIYGLCILWIFSGETQ 275

  Fly   294 APTYFRLIHHW----NIRATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRKLATFICC 354
            |.....|:..|    |..:...::..|.::..: ..|.::.|..:  :||::.........|:|.
pombe   276 AIAVNVLMGQWMKWSNKFSVAQINNYPTVITAV-GVVSTLGASVI--SDKLAGNPRWPFGLFLCV 337

  Fly   355 GTKGLIVLALA--------YFGYNATAAIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVS 411
            .|.....:.||        :|.|.|:.       .|....||.......:...:....|:|:.:.
pombe   338 ITTVSATILLAWNVPDGAKFFAYFASG-------CTYAGQAVWFSWANDICRDNDQERGVVVFLM 395

  Fly   412 GMIGGM----------PGFISP-FIVGQLTHNNQTIDAWKNVFLLTSLMLTGSGILYVLFSESKL 465
            .|...:          |...:| ||.|                 |..|::.| ||::|
pombe   396 NMCQNIWHIWWAPIMYPNTDTPRFIKG-----------------LIGLLVVG-GIVFV------- 435

  Fly   466 QPWNSGC----HQLPDSGLKELQNLGRDQDD---EEEKKPLK--SDHDKET 507
                |.|    .|:.|..:|......:|.||   |.|...||  ..:|:|:
pombe   436 ----SSCIVSYMQIRDKRIKRSIQDAKDFDDVFTEHESLELKKIGKNDEES 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	101/531 (19%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	88/432 (20%)
liz1	NP_001342731.1	MFS_1	37..401	CDD:311564	85/439 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050