DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NaPi-T and SPBC1683.12

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_595068.1	Gene:	SPBC1683.12 / 2539910	PomBaseID:	SPBC1683.12	Length:	482	Species:	Schizosaccharomyces pombe

Alignment Length:	526	Identity:	115/526 - (21%)
Similarity:	197/526 - (37%)	Gaps:	141/526 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TSNETHENSTDLAALAEMNERFSLER---W-------------FLDWANIPYE-----KNGFHWN 86
            ||.:..|.:.|...: |..|...|.|   |             |||.|||...     |......
pombe    14 TSVDISEGTFDDITI-EKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQ 77

  Fly    87 EKQQGALLGSFFWAHWTLQIPGGILATKYG-----TKLVFGWSNGIGVFCCFLIPIVSYWSYTGL 146
            ..|..|.:..|:..:.|.:.|..:|..|:|     :.::.|||. :.:|.||   :..|||   |
pombe    78 AYQYSAAVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSL-VTIFTCF---VRHYWS---L 135

  Fly   147 IILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYLGSSVGVALFYPIFGYII--------- 202
            ::.|:..|...|..:|.:.:..:......|:.|.: |||   ...:.|...||.:|
pombe   136 VLTRLLLGICEGGFFPCLSLYISMTYKREEQGKRL-AYL---YVCSCFSGAFGGLIATGLTKIPK 196

  Fly   203 --DWTRWEWVYYICGI---VGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKGP- 261
              ....|.|:|.|.|:   :..||.:   |.:.|.|:. .|..:...|.:.|......|...|.
pombe   197 SSGLPNWGWLYIIEGLISAISALWIL---FCLPDDPST-ARFLNPREKELMKIRAEQRQKYMGSP 257

  Fly   262 ----TPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRML 322
                |.::.......::::.|.|:.....|:.:.|..|:..:|...::..|..::|...:.:..:
pombe   258 NFDWTQFRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGI 322

  Fly   323 FAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVLVT-------V 380
            ..||..:.:|         |||:|           |..::.:.:||. |...|:|.|       |
pombe   323 SVYVICLLSD---------RTNIR-----------GWFIIGMNFFGL-AGFIILLATTNSAANYV 366

  Fly   381 ATMLHGAVSSGPLASMV---------DLSPNY-AGIVLGVSGMIGGMPGFI-------SPFIVGQ 428
            ||.|...    ||...|         :::|:| ....||.:..||.:.|.|       ||:.:|
pombe   367 ATYLIAL----PLYPTVALNITWINNNMAPHYRRATALGCNQTIGNLAGVIAGQVYRSSPYKLG- 426

  Fly   429 LTHNNQTIDAWKNVFLLTSLM---LTGSGILYVLFSESKLQPWNSGCHQLPDSGLKELQNLGRDQ 490
              |.          |.|...:   ||.:.:.:.|..::|::              :|:.| |...
pombe   427 --HG----------FALGCTVVGTLTATAMRFYLQRQNKIK--------------QEILN-GERV 464

  Fly   491 DDEEEK 496
            |:::|:
pombe   465 DEKKER 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	110/502 (22%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	94/439 (21%)
SPBC1683.12	NP_595068.1	MFS	47..417	CDD:119392	91/409 (22%)
SPBC1683.12	NP_595068.1	2A0114	50..417	CDD:273326	91/406 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050