DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and M117.1

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_502234.2	Gene:	M117.1 / 178112	WormBaseID:	WBGene00010918	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	481	Identity:	101/481 - (20%)
Similarity:	191/481 - (39%)	Gaps:	81/481 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RTVLWYMTF--IGFIVN-------YMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNE 62
            |.|::.:|:  :|.::|       .|:.:..|.||. ..||...|......|.|:.::|:|
Worm    77 RWVIFILTWLQLGSVMNCVDVFSFSMVYMEKNSTIA-AEAGLDDIYIYTLEEKSSLISAMA---- 136

  Fly    63 RFSLERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGI 127
                                       .|:|:|.:         |..:|..|||.:||..:::
Worm   137 ---------------------------IGSLIGMY---------PQNVLMQKYGPRLVLTFAS-- 163

  Fly   128 GVFCCFLIPIVSYW----SYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYLGSS 188
              ..|.::.....|    :|...::.|:|||.:....:..:..:.:||.|..|....::|..|.:
Worm   164 --LLCAVVTAFMPWALDTNYHVALVFRIFQGILYSADFGVVGYVCSKWSPIKEVGMSLAALSGFT 226

  Fly   189 VGVALF-YPIFGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLG 252
            ...|:. .|:.|:......|..:|||..|:..:..|.|.....|.|.:|..:...|.:.|.   |
Worm   227 AARAVIQLPLAGWTTSNVGWRPIYYILSIILFISTIIWFLFYRDDPEDHCLMTHHELQHIG---G 288

  Fly   253 ASIQGSKGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPH 317
            .:.:.....||::.:.|.:.||...||.:..|:..|..:.:...|::.: ..:|:|..:|:.:..
Worm   289 GTKRDKTKKTPYREVLTDKSVWAVWVAGFADIFASFVFLVYGAQYYQYL-GMDIQANAWLNSMKG 352

  Fly   318 LMRMLFAYVFSIFADYLLRT----DKMSRTNVRKL---ATFICCGTKGLIVLALAYFGYNATAAI 375
            .: .:...||:..|...:||    .|:...|...|   |.|:.     |:||......|   ..:
Worm   353 YL-FIGVRVFAGIASDRIRTLPEKSKLRLFNTISLQVPAFFLM-----LVVLLPREHPY---LHV 408

  Fly   376 VLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISP--FIVGQLTHNNQTIDA 438
            :.:|......|....|.......:|..::..|:|...:...:...:.|  |.:..|..:..:..:
Worm   409 ICITFYQASFGFNCGGFYKGAALISRQFSYFVIGYIQLFKSLATLLEPVLFSLLVLPGSEDSELS 473

  Fly   439 WKNVFLLTSLMLTGSGILYVLFSESK 464
            |.:.||:.:|.||.:..:|||.:.|:
Worm   474 WTSYFLIHALTLTVANTVYVLLARSE 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	101/481 (21%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	83/397 (21%)
M117.1	NP_502234.2	2A0114euk	66..499	CDD:129972	100/479 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820