DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and slc17a8

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_002936892.1	Gene:	slc17a8 / 100489470	XenbaseID:	XB-GENE-988965	Length:	588	Species:	Xenopus tropicalis

Alignment Length:	540	Identity:	162/540 - (30%)
Similarity:	258/540 - (47%)	Gaps:	55/540 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLER 68
            :..|.::..|:.:||.:::.||.||.:.||:|:           :.|:..:....||
Frog    72 IPKRYIIAMMSGLGFCISFGIRCNLGVAIVEMV-----------NNNTVYVDGKPEM-------- 117

  Fly    69 WFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCF 133
                      :|..|:|:.:..|.:.|||||.:...|||||.:|.|.....|||.:..:......
Frog   118 ----------QKAQFNWDPETVGLIHGSFFWGYIITQIPGGFIANKLAANRVFGAAIFLTSILNM 172

  Fly   134 LIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVGVALFYPI 197
            |||..:...:..:|.:||.||.:.|:.:|:.|.:.:||.||.|||:. .:::.||..|..:..|:
Frog   173 LIPSAARVHFGCVISVRVLQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPL 237

  Fly   198 FGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGS---- 258
            .|.::.:..|..|:||.|:.|..|::.|.....:|||.||.|...||.:||.|:|   :||
Frog   238 AGVLVQYIGWPSVFYIYGVFGMCWYVFWLLHATESPAAHPSITFEERTYIETSIG---EGSNLVT 299

  Fly   259 --KGPTPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRM 321
              |..||||...||.||:..:||.:...|..:.|:...|.||..:..:.|...|.||.:||::..
Frog   300 TGKFKTPWKKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGLLSAVPHMVMT 364

  Fly   322 LFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVL--VTVATML 384
            :...|....||:|.....:|.|.|||:..   ||..|:....|...||:.|.||.:  :.:|...
Frog   365 IIVPVGGQLADFLRSRKILSTTTVRKIMN---CGGFGMEATLLLVVGYSHTKAISISFLVLAVGF 426

  Fly   385 HGAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLM 449
            .|...||...:.:|::|.||.|::|:|..:|.:.|.:.|.|||.:| .|:|.:.|:||||:.:::
Frog   427 SGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KNKTREEWQNVFLIAAIV 490

  Fly   450 LTGSGILYVLFSESKLQPW-------NSGCHQLPDSGLKELQNLGRDQDDEEEKKPL--KSDHDK 505
            .....|.|.:|:..:.|.|       ...|..:.:..|.|...|..:......||..  .:.|..
Frog   491 HYSGVIFYGIFASGEKQEWADPESLSEDKCGIIDNDELAEETELNNESFTSSNKKSSYGSTIHSN 555

  Fly   506 ETPIVAEQETK-TKSDCDEK 524
            ||.....:..| |..|.||:
Frog   556 ETRRKGWRSKKGTTQDIDEQ 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	149/485 (31%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	131/392 (33%)
slc17a8	XP_002936892.1	2A0114euk	75..513	CDD:129972	148/473 (31%)
slc17a8	XP_002936892.1	MFS	81..502	CDD:119392	144/456 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010