DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NaPi-T and slc17a7b

DIOPT Version :9

Sequence 1:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	501	Identity:	160/501 - (31%)
Similarity:	251/501 - (50%)	Gaps:	52/501 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFL 71
            |.::..::.:||.:::.||.||.:.:|.|:         ..|....|
Zfish    62 RYIIAILSGLGFCISFGIRCNLGVAVVSMV---------NNHTVYRD------------------ 99

  Fly    72 DWANIPY-EKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLI 135
               ..|| .|..|.|:.:..|.:.|||||.:...|||||.:..|:....|||::.........:|
Zfish   100 ---GKPYIVKAQFSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMI 161

  Fly   136 PIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKF-VSAYLGSSVGVALFYPIFG 199
            |..:...:..:|::|:.||.:.|:::|:.|.:.|||.||.|||:. .:|:.||..|..:..|:.|
Zfish   162 PTAARMHFGCVILVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAG 226

  Fly   200 YIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKGP--- 261
            .::.::.|..|:|:.|..|..|::.|..:.::|||.||.|...|||:||.::|.| .|...|
Zfish   227 VLVQYSGWSSVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAIGES-AGLVNPLTK 290

  Fly   262 --TPWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFA 324
              |||:...||.||:..:||.:...|..:.|:...|.||..:..:.|...|.||.||||:..:..
Zfish   291 FNTPWRQFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVV 355

  Fly   325 YVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNAT--AAIVLVTVATMLHGA 387
            .:....||||...:.|:.||||||..   ||..||....|...|::.|  .||..:.:|....|.
Zfish   356 PIGGQLADYLRTHNLMTTTNVRKLMN---CGGFGLEATFLLVVGFSHTKGVAISFLVLAVGFSGF 417

  Fly   388 VSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLMLTG 452
            ..||...:.:|::|.||.|::|:|..:|.:.|.:.|.|||.:| .|:|.:.|:.|||:.||:..|
Zfish   418 AISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KNKTREEWQYVFLIASLVHYG 481

  Fly   453 SGILYVLFSESKLQPWNSGCHQLPDSGLKELQN-LGRDQ--DDEEE 495
            ..|.|.||:..:.|||..     |::..:|... ||.|:  |:.||
Zfish   482 GVIFYGLFASGEKQPWAE-----PENTSEEKCGILGEDELADETEE 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	152/475 (32%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	136/392 (35%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820