DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgm2b and AT1G70820

DIOPT Version :9

Sequence 1:	NP_610992.2	Gene:	Pgm2b / 36649	FlyBaseID:	FBgn0033969	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_177239.1	Gene:	AT1G70820 / 843419	AraportID:	AT1G70820	Length:	615	Species:	Arabidopsis thaliana

Alignment Length:	582	Identity:	126/582 - (21%)
Similarity:	204/582 - (35%)	Gaps:	142/582 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KTVISPQELLKTLE-LSGEEDLDL-----QIKNWVMWDRNEATLQQVTEAVRDQDWKALRVRLCH 66
            |||||...|..:|. :.....|..     .:|...:...|.....:||.:: |:|...:| ||.:
plant    13 KTVISKTALFSSLPGIVSRSFLTFAPASPSVKPLRIRSSNVTKFDEVTNSL-DEDMDQIR-RLQN 75

  Fly    67 RITYLTTGLRGVMRAGFDSLNDVVIIEVAQGICAYLVDAYPSIQKRQTQGVV---VGYD-----G 123
                 .:.:|||...| :....|.:...|....|.....:.:..:....||:   :|.|     |
plant    76 -----GSDVRGVALEG-EKGRTVDLTPAAVEAIAESFGEWVAATESNGNGVIKISLGRDPRVSGG 134

  Fly   124 RYNSKRFAQLIATVFLNNDFKVFLFTRMIPTPFIPFTVVTLQCLAGIVVTASHNVKEDNGIKVYW 188
            :.::..||.|.....|  .|.:.|.|  .|..|:...:...:..|.|::||||.....||:|.:.
plant   135 KLSTAVFAGLARAGCL--AFDMGLAT--TPACFMSTLLSPFEYDASIMMTASHLPYTRNGLKFFT 195

  Fly   189 SNGAQAMAPHDQRIHDYMMNNLEPKPSSWETSLVLDHPLVEDPYRQIYPLFYEALKTLI-PPIYL 252
            ..|. ..:|..::|.|........:.:...| |:...|...|..........|.:|..| .|.:.
plant   196 KRGG-LTSPEVEKICDLAARKYATRQTKVST-LIRTRPQQVDFMSAYSKHLREIIKERINHPEHY 258

  Fly   253 ETNECSQLRFIYTALHGVGYPFM--------REAFYQARLKPVIPVVEQKEADPEFPTLVKPNPE 309
            :| .....:.:..|.:|.|..|.        .:.|....|.|          |..||..: ||||
plant   259 DT-PLKGFQIVVNAGNGSGGFFTWDVLDKLGADTFGSLYLNP----------DGMFPNHI-PNPE 311

  Fly   310 EGKEALKLAIKKADAEHCTLVLAN--------DPDVDRLAVAELDPRGRWKLFNGNELGALLGWW 366
            .     |:|::...|    .||.|        |.||||..|  :|.:|  ...||::|.||:...
plant   312 N-----KIAMQHTRA----AVLENSADLGVVFDTDVDRSGV--VDNKG--NPINGDKLIALMSAI 363

  Fly   367 ALENYKTRTPKPAVTNCIMIATLVSSRILAAMARVEGFIFVEGMPSFPWMAHRALELEKSGRTVL 431
            .|:.:...|            .:..:|....:.|   ||                 .|:.||..|
plant   364 VLKEHPGST------------VVTDARTSMGLTR---FI-----------------TERGGRHCL 396

  Fly   432 FAFEECFGYM----FGMSLPDKDGIGAAMQLASMACYLRSTRNVTLIEKLREIYDTYGYHSSISS 492
            :.    .||.    .|:.| :||||...:.:                       :|.|:.:...:
plant   397 YR----VGYRNVIDKGVEL-NKDGIETHLMM-----------------------ETSGHGAVKEN 433

  Fly   493 VYMADSPETITSV---FDHLRNFTDEEGYPKFI--LDEEFEVVHIRDLTIGLDTSFSDGKAR 549
            .::.|....:..:   ...:|.....||....|  |:|..|.|.:|   :.:.:...|.||:
plant   434 HFLDDGAYMVVKIIIEMVRMRLAGSNEGIGSLIEDLEEPLEAVELR---LNILSEPRDAKAK 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2b	NP_610992.2	PTZ00150	26..621	CDD:240294	119/563 (21%)
Pgm2b	NP_610992.2	PGM2	67..607	CDD:100092	109/517 (21%)
AT1G70820	NP_177239.1	chaperonin_like	2..>94	CDD:295468	22/88 (25%)
		PLN02371	7..604	CDD:215211	126/582 (22%)
		PMM_PGM	73..592	CDD:100091	110/520 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1041556at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820