Protein Alignment Pgm2b and PGM3

DIOPT Version :9

• Sequence 1: NP_610992.2
• Gene: Pgm2b / 36649
• FlyBaseID: FBgn0033969
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001186846.1
• Gene: PGM3 / 5238
• HGNCID: 8907
• Length: 570
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 97/513 - (18%)
• Similarity: 161/513 - (31%)
• Gaps: 196/513 - (38%)

  Fly   169 GIVVTASHNVKEDNGIKVY----------WSNGAQAMAPHD----QRI--------------HDY 205
            |::||||||.:||||:|:.          |...|..:|..:    ||:              ..:
Human    86 GVMVTASHNPEEDNGVKLVDPLGEMLAPSWEEHATCLANAEEQDMQRVLIDISEKEAVNLQQDAF 150

  Fly   206 MMNNLEPKPSSWETS-LVLDHPLVEDPYRQIYPLFYEALKTLIPPIYLETNECSQLRF-IYTALH 268
            ::...:.:|||.:.| .|:|...|.......|.|       |..|         ||.: :|....
Human   151 VVIGRDTRPSSEKLSQSVIDGVTVLGGQFHDYGL-------LTTP---------QLHYMVYCRNT 199

  Fly   269 GVGY-PFMREAFYQARLKPVIPVVEQKEADPEFPTLVKPNPEEGKEALKLAIKKADAEHCTLVLA 332
            |..| ....|.:||...|..:.:.:|.....:....:|.:...|..||||    .:.||..
Human   200 GGRYGKATIEGYYQKLSKAFVELTKQASCSGDEYRSLKVDCANGIGALKL----REMEHYF---- 256

  Fly   333 NDPDVDRLAVAELDPRGRWKLFNGNELGALLGWWALENYKTRTPKPAVTNCIMIATLVSSRILAA 397
                ...|:|         :|||....|.|       |:.          |
Human   257 ----SQGLSV---------QLFNDGSKGKL-------NHL----------C-------------- 277

  Fly   398 MARVEGFIFVEGMPSFPWMAHRALELEKSGRTVLFAFEECFGYMFGMSLPDKDGIGAAMQLASMA 462
                 |..||:.....|    :.:|::.:.|...|.             .|.|.|
Human   278 -----GADFVKSHQKPP----QGMEIKSNERCCSFD-------------GDADRI---------- 310

  Fly   463 CYLRSTRNVTLIEKLREIYDTYGYHSSISSVYMADSPETITSVFDHLRNFTDEEGYPKFILDEEF 527
                                .|.||.:....::.|..:..|.:...|:....|.|
Human   311 --------------------VYYYHDADGHFHLIDGDKIATLISSFLKELLVEIG---------- 345

  Fly   528 EVVHIRDLTIG-LDTSFSDGKA--------RMPV-------------TPDAQLITFTFTNGYVVT 570
                 ..|.|| :.|::::|.:        ::||             ..:..:..:...||:...
Human   346 -----ESLNIGVVQTAYANGSSTRYLEEVMKVPVYCTKTGVKHLHHKAQEFDIGVYFEANGHGTA 405

  Fly   571 LRSAPNDIKIKLNAEICGLPEEKQWEELHDKLNRMTNAVVEEFLQPEENGLTDASTIQ 628
            |.|...::|||.:||        |.|:...|..:|...:::.|.|...:.::|...|:
Human   406 LFSTAVEMKIKQSAE--------QLEDKKRKAAKMLENIIDLFNQAAGDAISDMLVIE 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgm2b	NP_610992.2	PTZ00150	26..621	CDD:240294	95/504 (19%)
		PGM2	67..607	CDD:100092	93/490 (19%)
PGM3	NP_001186846.1	PGM3	50..555	CDD:100088	97/513 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1109
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900