DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spred and Enah

DIOPT Version :9

Sequence 1:NP_001260979.1 Gene:Spred / 36643 FlyBaseID:FBgn0020767 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_030102994.1 Gene:Enah / 13800 MGIID:108360 Length:860 Species:Mus musculus


Alignment Length:381 Identity:83/381 - (21%)
Similarity:125/381 - (32%) Gaps:164/381 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 RAQVMTRDESTEGWLPLAGG--GLANVSIRKRARLSPLASGHDYIIYGQRISDQSVILSCVINRD 76
            ||.||..|::.:.|:| |||  |.:.|.|...      ...:.:.:.|::|.|..|:::|.|.:.
Mouse    41 RAAVMVYDDANKKWVP-AGGSTGFSRVHIYHH------TGNNTFRVVGRKIQDHQVVINCAIPKG 98

  Fly    77 LKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDG--LAKSNPT--------- 130
            |||.:...|||.||..:|..||.|.:..||..|...::.|. |:::.  .|:|..|         
Mouse    99 LKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHAL-EVLNSQEAAQSKVTATQDSTNLR 162

  Fly   131 -IIC-----PPLTKYDSVGEDDVFMTLDLP----------------------------------- 154
             |.|     |.|.:.:|          .||                                   
Mouse   163 CIFCVFYLGPTLPRQNS----------QLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMER 217

  Fly   155 ------------VESESLQKIHSSPEGSEKSH--------------------------------- 174
                        :|.|.|::.....:..|:.|                                 
Mouse   218 ERLERERLERERLERERLEQEQLERQRQEREHVERLERERLERLERERQERERERLEQLEREQVE 282

  Fly   175 ----KSVSN---NSDSE----KLP----------PPPIH--YISTDKTSATTSPPD------APP 210
                :.:||   :|||.    .||          |||.:  .||...:.||   ||      .||
Mouse   283 WERERRMSNAAPSSDSSLSSAPLPEYSSCQPPSAPPPSYAKVISAPVSDAT---PDYAVVTALPP 344

  Fly   211 ASAAPSPA---TAGQIAASENYSYVTLTAVHHDY--NYPVVDQPVGAQVLNARRES 261
            .|..|:|.   .|.:.|.|       |.:..|..  :|..|.:|:..   |:|..|
Mouse   345 TSTPPTPPLRHAATRFATS-------LGSAFHPVLPHYATVPRPLNK---NSRPSS 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SpredNP_001260979.1 EVH1_SPRED-like 9..122 CDD:269978 36/109 (33%)
Sprouty 315..413 CDD:282994
EnahXP_030102994.1 EVH1_Ena_VASP-like 36..143 CDD:269918 36/109 (33%)
PHA03247 <356..576 CDD:223021 11/45 (24%)
VASP_tetra 823..857 CDD:370114
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167832310
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4590
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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