DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10151 and Zscan29

DIOPT Version :9

Sequence 1:	NP_001137670.1	Gene:	CG10151 / 36639	FlyBaseID:	FBgn0033960	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001277748.1	Gene:	Zscan29 / 99334	MGIID:	2139317	Length:	834	Species:	Mus musculus

Alignment Length:	307	Identity:	63/307 - (20%)
Similarity:	123/307 - (40%)	Gaps:	83/307 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KSSARIKKRRSEAAAATYPVPSAP----------AQTVS---NG------SAATANPASATSTPG 49
            ||..::|        :.:|..:.|          ||.:|   ||      .:|.|...:.|..||
Mouse   300 KSYRKVK--------SGHPPDTCPFFEEMEALMSAQVISLPINGLEEAASHSAQAGSDAETEKPG 356

  Fly    50 --------------------NGATNPCQSSSKKQSFVGRNP---NFDTDETKLLIQLWGDPKLQR 91
                                :....|....:.....:.|:|   ::..:|||..:.:..:.:...
Mouse   357 QRDWQHEDGEEAIAERSDSDDPEATPQDPDNPPAPVLFRSPSGVHWGYEETKTYLAILSETQFYE 421

  Fly    92 TLITTHKKHAVICQLAAKMQEYGYHRSPEEITTRIKNLKCFYNRLKKDKECGGQSTDSEPSWKHF 156
            .|...|:...:...:|.::.|||:.|:||:..|:.|:|:..|.::|     .||:.::.|   .|
Mouse   422 ALQNCHRNSQLYGTVAERLWEYGFLRTPEQCRTKFKSLQTSYRKVK-----NGQALETCP---FF 478

  Fly   157 AEMDAIMTRPIFSVRPNEVPAPSLKYQLEQALEEHAERRKRRLANGEELSESDNEEDD------- 214
            .||||:::..:.:...::....::...|::..|...|::      .|:..|..::|||
Mouse   479 EEMDALVSAQVAAPPSDDQEKETVSCCLQRTSEAEPEKQ------DEDTEEDSDDEDDTEIPPEA 537

  Fly   215 MLLSALVSKNKDTGGRKELEAGCLEADSDMNEESFSKRRKVSADVEV 261
            ::..|.|.....:|    .|||.      .|||  :.:|.:|.:|::
Mouse   538 VITRAPVLFQSPSG----FEAGF------ENEE--NSKRDISEEVQL 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10151	NP_001137670.1	Myb_DNA-bind_4	69..158	CDD:290549	22/91 (24%)
Zscan29	NP_001277748.1	SCAN	13..123	CDD:128708
		SCAN	13..101	CDD:280241
		Myb_DNA-bind_4	238..319	CDD:290549	5/26 (19%)
		Myb_DNA-bind_4	399..480	CDD:290549	21/88 (24%)
		COG5048	<663..823	CDD:227381
		zf-C2H2	665..687	CDD:278523
		C2H2 Zn finger	667..687	CDD:275368
		zf-H2C2_2	680..702	CDD:290200
		C2H2 Zn finger	695..715	CDD:275368
		zf-H2C2_2	707..732	CDD:290200
		C2H2 Zn finger	723..743	CDD:275368
		zf-H2C2_2	735..760	CDD:290200
		C2H2 Zn finger	751..771	CDD:275368
		zf-H2C2_2	763..787	CDD:290200
		zf-C2H2	777..799	CDD:278523
		C2H2 Zn finger	779..799	CDD:275368
		C2H2 Zn finger	807..827	CDD:275368
		zf-C2H2	807..827	CDD:278523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12111
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S9777
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860