DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10151 and CG10494

DIOPT Version :9

Sequence 1:	NP_001137670.1	Gene:	CG10151 / 36639	FlyBaseID:	FBgn0033960	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_726079.1	Gene:	CG10494 / 37453	FlyBaseID:	FBgn0034634	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	96/507 - (18%)
Similarity:	172/507 - (33%)	Gaps:	153/507 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 TSTPGNGATNPCQSSSKKQSFVGRNPNFDTDETKLLIQLWGDPKLQRTLITTHKKHAVICQLAAK 109
            :.|.|:.|.:   :|....:.|.| ..:...|..||:.|.....|:..|:  .|::|.:.:|.:|
  Fly   158 SETEGDDALD---ASGSSVNIVAR-CKWAEGEVDLLLDLIHTLGLRAALL--QKRNAKVFKLLSK 216

  Fly   110 -MQEYGYHRSPEEITTRIKNLKCFYNRLKKDKECGGQSTDSEPSWKHFAEMDAIMTRPIFSVRPN 173
             |.:...|:..|::..:.:.|:..||::|         ..:..:::||..|..::.       |.
  Fly   217 EMAKRNCHKGAEKLRIKFQQLRRLYNKVK---------NGTGKTFEHFEAMRLVLD-------PT 265

  Fly   174 EVPAPSLKYQLEQALEEHAERRKRRLANGEELSESDNEEDDMLLSALVSKNKDTGGR----KELE 234
            |.         |.|.:..||..... |:..:.::||.||.|        .::.:|..    :|::
  Fly   266 EE---------EAAADAEAEAHLSS-ASDSDFNDSDEEEGD--------ASQRSGAHFWTDEEVD 312

  Fly   235 AGCLEADSDMNEESFSKRRKVSADVEVDIGEALTSPCIKIEPGQEVETAAATSTVEPQQEEED-D 298
            :..|....:....:....||.:....|.|...|....||..|.|.............:.:|.. |
  Fly   313 SFLLIIRDNGFFRALDGSRKRNFQTLVHISNILAKQDIKRTPHQLRNKLRLLCKRHREAKEHGLD 377

  Fly   299 DCMILPQPKEEPIDVDAADDPPIEKSSSSTTNTSTLADMLQGNKPSNLLPFTGANVIIPASITTT 363
            :..|||:..|.   .|.....|.|...|:      ::.:::.:|||.|.|
  Fly   378 NVRILPRHFEL---FDELIQAPRENRESA------ISRLIRISKPSFLKP--------------- 418

  Fly   364 TAGTSATTQSSTTTSSKLQGGKISLVPANFLMQSKLPAAAGPSPMANAKGAAPQIQLLQSAINQG 428
                               .||.| ||..                :::..::....||::|
  Fly   419 -------------------PGKPS-VPLE----------------SDSDNSSSTCDLLRAA---- 443

  Fly   429 ARLMISGSAAAPAQPSNAGLVATAPGGVKFVLVNAEQAKAAAAAAAVGKSTASLPLSTAQAQVQA 493
                                 |.:...|..:.:.||.....|..|.:          ..|.|:.|
  Fly   444 ---------------------ADSEDYVDAIEMEAEPTPIEALTAII----------EGQKQLLA 477

  Fly   494 AVQQQQQKLHQSLQQEQHHQQHIQLEK--EESRHDHEKGRKDLQTKRHMTSM 543
                |.:..::|..::|..|||..||:  |....|.|      :|.|.::.|
  Fly   478 ----QIKTTNESFLRQQREQQHQFLEQVSELMHRDRE------ETLRRISEM 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10151	NP_001137670.1	Myb_DNA-bind_4	69..158	CDD:290549	19/89 (21%)
CG10494	NP_726079.1	Myb_DNA-bind_4	44..123	CDD:290549
		Myb_DNA-bind_4	178..257	CDD:290549	20/90 (22%)
		Myb_DNA-bind_4	303..391	CDD:290549	17/90 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12111
eggNOG	1	0.900	-	-		E1_KOG4282
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810