DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10151 and paics

DIOPT Version :9

Sequence 1:	NP_001137670.1	Gene:	CG10151 / 36639	FlyBaseID:	FBgn0033960	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_955831.1	Gene:	paics / 321193	ZFINID:	ZDB-GENE-030131-9762	Length:	425	Species:	Danio rerio

Alignment Length:	447	Identity:	86/447 - (19%)
Similarity:	138/447 - (30%)	Gaps:	147/447 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 TRPIFSVRPNEVPAPSLKYQLEQALEEHAERR-----KRRLANGEELSESDNEEDDMLLSALVSK 223
            |:.||.:.  :.|...|....:|....:|.|:     |..:||..........:|..|.:|.|.:
Zfish    18 TKQIFEIL--DEPGHVLVQSKDQITAGNAVRKDQMEGKAAIANKTTSCVFKLLQDAGLKTAFVRQ 80

  Fly   224 NKDTG----------------------------GRKE------LEAGCLEADSDMNEESFSKRRK 254
            :.||.                            |.||      |:......|...|:..:|:.:.
Zfish    81 HSDTAFVASRCEMIPIEWVCRRIATGSFLKRNPGVKEGYRFTPLKMEMFFKDDANNDPQWSEEQL 145

  Fly   255 VSAD----------VEVDIGEALTSPCIKIEPGQEVETAAATSTVEPQQEEEDDDCMILPQPKEE 309
            ::|.          .||||....|....::     :|.|.||           .||.::
Zfish   146 LAAGFDLAGLTIGRCEVDIMSKSTVAIFEV-----LEKAWAT-----------QDCTLV------ 188

  Fly   310 PIDVDAADDPPIEKSSSSTTNTSTLADMLQGNKPSNLLP------------FTGANVIIPAS--- 359
                    |..||...:.||....|||::. |....|.|            :.....:.|.:
Zfish   189 --------DMKIEFGVNVTTKEIVLADVID-NDSWRLWPAGDRSQQKDKQVYRDLKEVTPEAMQM 244

  Fly   360 ---------------ITTTTAGTSATTQSSTTT---SSKLQGGKISL-VPANFLMQSKLPAAAGP 405
                           :.:...|.......||:.   ..|::....|. :|.:..:.|   |..||
Zfish   245 VKRNFEWVAERVKLLLESQARGRVVVMMGSTSDVAHCEKIRKACASYGIPCHLRVNS---AHKGP 306

  Fly   406 SPMANAKG-----AAPQIQLLQSAINQGARLMISGSAAAP------------AQPSNAGLVATAP 453
            ......|.     ..|.|.:..:..:.|...::||:.|.|            ||...:.|  ..|
Zfish   307 DETLRIKAEYEGDGEPTIFVAVAGRSNGLGPVMSGNTAYPVINCPPVTPDWGAQDIWSSL--RMP 369

  Fly   454 GGVKFVLVNAEQAKAAAAAAAVG--------KSTASLPLSTAQAQVQAAVQQQQQKL 502
            .|:....|.:.:|.|..||..:|        |..||: |:|..:..||..:.|...|
Zfish   370 SGLGCSTVLSPEAAAQFAAQILGLNNHLIWAKLRASM-LNTWVSLKQADKKMQDCSL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10151	NP_001137670.1	Myb_DNA-bind_4	69..158	CDD:290549
paics	NP_955831.1	SAICAR_synt_Ade5	7..258	CDD:133471	48/272 (18%)
paics	NP_955831.1	purE	268..421	CDD:273474	35/158 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11643
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910