Protein Alignment jef and AgaP_AGAP002043

DIOPT Version :9

• Sequence 1: NP_001246323.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: XP_001238414.3
• Gene: AgaP_AGAP002043 / 4576905
• VectorBaseID: AGAP002043
• Length: 560
• Species: Anopheles gambiae
• Alignment Length: 619
• Identity: 134/619 - (21%)
• Similarity: 234/619 - (37%)
• Gaps: 150/619 - (24%)

  Fly   112 ELIPVKSFYFFFYAAFGSLFPLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYADRCRQG 176
            :|:.:|...|..:.|..:|.|.:.::.:.:|:...:...:.....|...||.|..|...||..:.
Mosquito    17 QLVQLKVTLFLLFGATSALTPYLTIHMQSIGLTVEEVASVYLTLLFTSCLSPPLTGYLIDRFGRY 81

  Fly   177 KRLLLGSLACWVLFTIPLSFIRPEAINCIERRNATDFVLTYTRTKRDLSAMYEQEHLDMGTGT-- 239
            |.:||.|        |.|:.:....|:.|..||.   ::||......|:          |.|.
Mosquito    82 KPVLLTS--------IVLNAVSHHLIHFIPARNV---IVTYRSWNVSLA----------GDGAAL 125

  Fly   240 ------MPADEALEEAEAAHSRHKRSLLLPRIDAGISPVHINFVSNYD----DKYHRDYVTPIFS 294
                  .|....|..:.:::|    |..||           .::|..|    |....|...|..|
Mosquito   126 LLHGTYCPLQGYLNSSCSSNS----STSLP-----------TYLSASDISCADLLIPDCALPALS 175

  Fly   295 ----SMVYRTP---DIQKAFFLLLLVILIGEFFSAPAITLADSAVITLLGEDADKYGHQRMFGSL 352
                |::...|   :....|:..|.|..:.....|..:|:.|...:.::.:....:|.::::.|:
Mosquito   176 AGTLSLLEPIPPASEYDATFWTYLAVRFVAASMLASTLTITDPIALDMVEQHGGDFGREKLYSSV 240

  Fly   353 GWGISMFLVGIALDHSTSFSNHPCGAGNKEKNYNICFSIFSVLMTCAIISASKITFKYDPIDEQL 417
            |..|...|.|:.:|..:|      |:|..|..|...|..:.:|:..:::|.|.:     ||..::
Mosquito   241 GMAIFTPLTGLMIDAWSS------GSGPTETVYTPAFYTYDLLLLGSLVSVSLM-----PIGRKI 294

  Fly   418 AAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAVGSGSAASGACAGGVSSFLATGHQPQPHIGAE 482
            .::...|  |.|:            .|.||.                |.:|||
Mosquito   295 PSESVMQ--DTNR------------LLRLPP----------------VLAFLA------------ 317

  Fly   483 SKVFAQTAKELPEWMTVLTHFKDLKTASFLFVAWFMGFGIGLIFTFLFWHLQDYGGTPTLFGVAS 547
                                        |||:   :|...|.|.::||..::..|....|.|:..
Mosquito   318 ----------------------------FLFL---LGNFWGFIESYLFVIMKAMGSPNYLLGLTY 351

  Fly   548 VINHVSEIFAYFFSFRLITQIGHVKVLCLGLIGNVLRFLYISYLTNPWMVLPFELMQGITHAAVW 612
            .:..|:.|...:...|:..::|||.:|.:....:.||.|..|::|||:...|.||.:.|:...:|
Mosquito   352 TVGTVASIPMMYLLERITQRVGHVNLLVVAFFAHALRILGYSWITNPYWCFPIELNEAISCYFMW 416

  Fly   613 AASCSYIAHNTPKHLRASAQGVLQGIHHGLGRGCGAIIGGMFVTYYGTTTTFRWYG---IAC--L 672
            ..:.:|.|...|..|.|:..|:...:|..||:|.||.:||..:...|....||:.|   :.|  |
Mosquito   417 VVATTYCAVLAPNSLVATLIGIAGMVHFCLGKGVGAFVGGFLIARVGLVLAFRYVGYMAVGCGVL 481

  Fly   673 FVLGFFIFVNFYRKEQGFISEIPVTEDPHQVAEE 706
            :.|...::::.|...     .:| ..||.:..||
Mosquito   482 YKLVHLLWLHRYDGR-----ALP-DRDPVRAVEE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_001246323.1	MFS	125..187	CDD:304372	15/61 (25%)
		MFS	508..>681	CDD:119392	51/177 (29%)
		MFS_1	511..>701	CDD:284993	54/194 (28%)
AgaP_AGAP002043	XP_001238414.3	MFS_1_like	18..92	CDD:289593	19/81 (23%)
		MFS_1	<193..452	CDD:284993	74/342 (22%)
		MFS	<325..482	CDD:119392	45/156 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3762
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005424
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810