Protein Alignment jef and mfsd6b

DIOPT Version :9

• Sequence 1: NP_001246323.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_001315145.1
• Gene: mfsd6b / 447825
• ZFINID: ZDB-GENE-040912-84
• Length: 807
• Species: Danio rerio
• Alignment Length: 676
• Identity: 257/676 - (38%)
• Similarity: 361/676 - (53%)
• Gaps: 125/676 - (18%)

  Fly   107 ASTERELIPVKSFYFFFYAAFGSLFPLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYAD 171
            |..:..|:..|.||||||:|:|||.||:.||:||:||.|.|.|:|||:|.|:||.||||||..||
Zfish    65 ARIDNRLLISKIFYFFFYSAYGSLHPLLAVYYKQLGMTPTQSGLLVGIRYFIEFCSAPFWGFVAD 129

  Fly   172 RCRQGKRLLLGSLACWVLFTIPLSFIRPEAINCI-------ERRNATDFVL--TYTRTKRDLSAM 227
            |.::||.:||.|:.|||:|...:.|::|.|::|:       ...|.|::..  .:||.:|.|:
Zfish   130 RFKKGKAVLLFSVLCWVVFNCGIGFVKPAAMSCVSVDPTVQSPVNFTNYTHAGNHTRQRRYLT-- 192

  Fly   228 YEQEHLDMGTGTMPADEALEEAEAAHSRHKRSLLLPRIDAGI--SPVHINFVSNYDDKYHRDYVT 290
                  :......|..:.:..|...|||:.||.......|..  |.|.|:..||...........
Zfish   193 ------EDAYANPPLSQPILAAYRPHSRYIRSANTNTTSAPFRNSTVDISMASNLTTMSPSATKV 251

  Fly   291 PIFSS----------------MVYRTPDIQKAFFLLLLVILIGEFFSAPAITLADSAVITLLGED 339
            |:.|:                :::....:...|.|:||||:|||||||||:|:.|:..:..||::
Zfish   252 PLKSTSTMETQAITAKVKQYIIIFNKEQVDTIFLLILLVIIIGEFFSAPAVTIVDTVTLQYLGQN 316

  Fly   340 ADKYGHQRMFGSLGWGISMFLVGIALD--HSTSFSNHPCGAG---NKEKNYNICFSIFSVLMTCA 399
            .|:||.|||:|||||||:|..|||.:|  |.|.|..   |.|   ...|||.|.|.:|.||||.|
Zfish   317 RDRYGLQRMWGSLGWGIAMLSVGIWIDNTHITIFIQ---GLGCVLPDYKNYQIAFIVFGVLMTSA 378

  Fly   400 IISASKITFKYDPIDEQLAAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAVGSGSAASGACAGG 464
            :|.|::  |.:|        .:..|..:...:.|:..:.|:..:::.|.    |.|..:..|.
Zfish   379 LIVATQ--FHFD--------NRAYQSDEEEDKKEDVEIPQVIQEVSSPE----SSSDDAPVCP-- 427

  Fly   465 VSSFLATGHQPQPHIGAESKVFAQTAKELPEWMTVLTHFKDL-------KTASFLFVAWFMGFGI 522
                 .|..|..|                         ||||       :..:.||||||||||.
Zfish   428 -----ETNPQHFP-------------------------FKDLFRIICGVRYGTVLFVAWFMGFGY 462

  Fly   523 GLIFTFLFWHLQDYGGTPTLFGVASVINHVSEIFAYFFSFRLITQIGHVKVLCLGLIGNVLRFLY 587
            |.:||||||||:|..||.||||:.||::|:||:.|||.|.:||..:||::||.:||..|..|:||
Zfish   463 GFVFTFLFWHLEDLKGTTTLFGICSVLSHISELAAYFISHKLIELVGHIRVLYIGLACNTARYLY 527

  Fly   588 ISYLTNPWMVLPFELMQGITHAAVWAASCSYIAHNTPKHLRASAQGVLQGIHHGLGRGCGAIIGG 652
            ||||.|.|:|||.|::||:|||:||||..||::...|..||.||||:|||:|.||||||||::||
Zfish   528 ISYLENAWIVLPMEVLQGLTHASVWAACISYLSAAVPPALRTSAQGILQGLHLGLGRGCGAMLGG 592

  Fly   653 MFVTYYGTTTTFRWYGIACLFVLGFFIFVNFY-----RKEQGFISE-IPVTEDPHQVAEETSHLA 711
            :||.::|...|||..|:|.|..|..|..:.:.     .|:...::| ||
Zfish   593 VFVNFFGAAETFRGLGMASLVTLLIFSLIQWLLGQNEEKKGAMLAENIP---------------- 641

  Fly   712 PHGVPSNPIPRA----LSNSRLNEMN 733
               |||:|:|.|    :.|...::.|
Zfish   642 ---VPSSPVPIATIDLVQNQSTSQPN 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_001246323.1	MFS	125..187	CDD:304372	36/61 (59%)
		MFS	508..>681	CDD:119392	100/172 (58%)
		MFS_1	511..>701	CDD:284993	104/195 (53%)
mfsd6b	NP_001315145.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593618
Domainoid	1	1.000	396	1.000	Domainoid score	I728
eggNOG	1	0.900	-	-		E1_KOG3762
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1802
OMA	1	1.010	-	-		QHG47931
OrthoDB	1	1.010	-	-		D290600at33208
OrthoFinder	1	1.000	-	-		FOG0005424
OrthoInspector	1	1.000	-	-		otm24248
orthoMCL	1	0.900	-	-		OOG6_104266
Panther	1	1.100	-	-	O	PTHR16172
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4198
SonicParanoid	1	1.000	-	-		X4359
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800