Protein Alignment jef and Mfsd6l

DIOPT Version :9

• Sequence 1: NP_001246323.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_001099257.1
• Gene: Mfsd6l / 287414
• RGDID: 1307767
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 640
• Identity: 138/640 - (21%)
• Similarity: 238/640 - (37%)
• Gaps: 126/640 - (19%)

  Fly   132 PLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYADRCRQGKRLLLGSL-----ACWVLFT 191
            |.:.:|.:|:|:.....|||:|.:..:.....||....|.|.::.:..|.|||     |..::..
  Rat    32 PFLTLYLRQLGVAAPWVGILMGTKHLIAACWTPFCAFLARRYQKRRMFLTGSLLGSAGASLLMVL 96

  Fly   192 IPLS--FIRPEAINCIERRNATDFVLTYTRTKRDLSAMYEQEHLDMGTGTMPADEALEEAEAAHS 254
            :|.:  .:.....|...:...|...|..|:|....||.....:...|..::|.           |
  Rat    97 VPPADRNLGNHFCNGSSKVATTVLPLVVTQTVTMTSAQGSVPNHWAGAPSLPG-----------S 150

  Fly   255 RHKRSLLLPRIDAGISPVHINFVSNYDDKYHRDYVTPIFSSMVYRTPDIQKAFFLLLLVILIGEF 319
            ||.|:|     |....|   |......::..|...|.:..|:.                   |..
  Rat   151 RHTRAL-----DTSGFP---NGSGKTQERTLRGLQTYLVGSVE-------------------GVR 188

  Fly   320 FSAPAITLADSAVITLLGEDADKYGHQRMFGSLGWGISMFLVGIALDHSTSFS---------NHP 375
            .:|.|:.|..|.    |.|::.| |...:..:   .:|:......|....:.|         ||.
  Rat   189 TTAQALNLVTSG----LRENSQK-GTSEVSNA---NLSLLPGSTTLGGPVNVSKTQGDIQTHNHT 245

  Fly   376 CGAGNKEKNYNICFSIFSVLMTCAIISASKITFKYDPIDEQLA---AQQQAQFVDPNKRAEEESM 437
            .    |...:.:..| |..|:...:::|        |: ||:|   ..:...|||...|.::..:
  Rat   246 L----KGSQWTVILS-FGFLVFWELLAA--------PL-EQVADDSLYEYLDFVDAADRNKDLWV 296

  Fly   438 NQLAAQLNLPSLAVGSGSAASGACAGGVSSFL-ATGHQPQPHIGAESKV-----FAQTAKELPEW 496
            .:|        |.:.:|.....|....:..|| |.|.|...:..:.|.|     ...||..:|..
  Rat   297 WRL--------LGISAGVCGIAALVEHLECFLVANGPQGVIYFYSYSLVSTLALAVSTAFPVPID 353

  Fly   497 MTVLTHFKDLKTASFL----------FVAWFMGFGIGLIFTFLFWHLQDYGGTPTLFGVASVINH 551
            ......:|.:|..|.:          |..:::|.....:..|||||::|:|.:..:.|.:.|:..
  Rat   354 QQQRPSYKAIKALSLVRDDSRLILLAFTVFWIGATTSTVQNFLFWHMKDHGSSDLVMGFSVVLGL 418

  Fly   552 VSEIFAYFFSFRLITQIGHVKVLCLGLIGNVLRFLYISYLTNPWMVLPFELMQGITHAAVWAASC 616
            :.||..:.|...|:.::..|.||.|||....|:.||.:::.:.|.|||.:::..|:..|:|.|..
  Rat   419 LGEILFHPFRTSLLRKLSRVGVLGLGLGCLALQMLYYAFIWSWWSVLPVQILSAISSGALWWAVG 483

  Fly   617 SYIAHNTPKHLRASAQGVLQGIHHGLGRGCGAIIGGMFVTYYGTTTTFRWYGIACLFVLGFFIFV 681
            :.|.......:..|...:.:|..:..|...|:.:||.....:|....::    ||..||..::.|
  Rat   484 ASIGDLASSRMERSLNTLFRGHLYESGCSLGSFVGGFVALRFGVAVLYQ----ACCVVLLLWLAV 544

  Fly   682 NFYRKEQGFISEIPVTEDPHQVAEETSHLAPHGVPSNPIPRALSNSRLNEMNPNG 736
                    |:|..|......:: ..:..||..|          |||..:|....|
  Rat   545 --------FLSIQPRLPQEQRI-NYSKLLAMEG----------SNSSDSEQGSEG 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_001246323.1	MFS	125..187	CDD:304372	17/59 (29%)
		MFS	508..>681	CDD:119392	45/182 (25%)
		MFS_1	511..>701	CDD:284993	48/199 (24%)
Mfsd6l	NP_001099257.1	MFS	<28..87	CDD:304372	16/54 (30%)
		MFS	375..>552	CDD:119392	48/188 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3762
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810