Protein Alignment jef and Mfsd6l

DIOPT Version :10

• Sequence 1: NP_610983.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_666116.1
• Gene: Mfsd6l / 215723
• MGIID: 2384904
• Length: 586
• Species: Mus musculus
• Alignment Length: 620
• Identity: 124/620 - (20%)
• Similarity: 214/620 - (34%)
• Gaps: 183/620 - (29%)

  Fly   132 PLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYADRCRQGKRLLLGSLACWVLFTIPLSF 196
            |.:.:|.:|:|:.....|||:|.:..:.....||....|.|.::.:..|.|||......::.:..
Mouse    32 PFLTLYLRQLGVAAPLVGILMGTKHLIATCWIPFCAFLAKRYQKRRMFLTGSLLSSAGASLLMVL 96

  Fly   197 IRPEAINCIERRNATDFVLTYTRTKRDLSAMYEQEHLDMG---TGTMPADEALEEAEAAHSRHKR 258
            :.|     ::|.....|....:|....:        |.:|   |..|...:.........|||.|
Mouse    97 VPP-----VDRNLVNHFCNGSSRVATTI--------LPLGVTQTVIMTPTQGSGAPNLPGSRHTR 148

  Fly   259 SL----------------------------------------------------------LLPRI 265
            :|                                                          |||..
Mouse   149 ALDTSGFPNGSEGTFSGLQTYLVGSVEGARTTTQGLHLVTSGLRDNSQKGTFEVGNVTLNLLPGS 213

  Fly   266 DAGISPVHINFVSNYDDKYHRDYVTPIFSSMVYRTPDIQKAFFLLLLVILIGEFFSAPAITLADS 330
            .|...||:::       |...|..||..||.  .:|   ..|.|.|.|::..|..:||...:||.
Mouse   214 TALGGPVNLS-------KPQGDTQTPDHSSK--GSP---WTFILSLGVVVFWELLAAPLEQVADD 266

  Fly   331 AVITLLGEDADKYGHQRMFGSLGW-----GISMFLVGIA--LDHSTSF--SNHPCGAGNKEKNYN 386
            ::...| :..|.....|..    |     |:|..:.|||  :.|....  :|.|.|.
Mouse   267 SLYEYL-DFVDATDRNRDL----WVWKLLGVSAGVCGIAALVGHLECLLVANGPQGV-------- 318

  Fly   387 ICFSIFSVLMTCAIISASKITFKYDPIDEQLAAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAV 451
            |.|..:|::.|.|:..::....   |||     |||.    |:.:|             :.:|::
Mouse   319 IYFYSYSLVSTLALAVSTAFPV---PID-----QQQG----PSYKA-------------IKALSL 358

  Fly   452 GSGSAASGACAGGVSSFLATGHQPQPHIGAESKVFAQTAKELPEWMTVLTHFKDLKTASFLFVAW 516
            ..|                                                  |.:.....|..:
Mouse   359 IRG--------------------------------------------------DSRLILLAFTVF 373

  Fly   517 FMGFGIGLIFTFLFWHLQDYGGTPTLFGVASVINHVSEIFAYFFSFRLITQIGHVKVLCLGLIGN 581
            ::|.....:..|||||::|:|.:..:.|.:..::.:.||..:.|...|:.::..|.||.|||...
Mouse   374 WIGATASTVQDFLFWHMKDHGSSELVMGFSVALSLLGEILFHPFRTSLLRKLSRVGVLGLGLGCL 438

  Fly   582 VLRFLYISYLTNPWMVLPFELMQGITHAAVWAASCSYIAHNTPKHLRASAQGVLQGIHHGLGRGC 646
            .|:.||.:::.:.|.|||.:::..|:..|:|.|..:.|.......:..|...:.:|..:|.|...
Mouse   439 ALQVLYYAFIWSWWSVLPVQILSTISSGALWWAVGASIEDLAFSGMERSLGTMFRGHFYGSGCSL 503

  Fly   647 GAIIGGMFVTYYGTTTTFRWYGIACLFVLGFFIFV 681
            |:.:||..|.::|....:....:..|..|..|:.:
Mouse   504 GSFVGGFVVLHFGIAVLYEACCVVLLLWLALFLSI 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_610983.1	MFS_MFSD6	128..683	CDD:340893	124/620 (20%)
Mfsd6l	NP_666116.1	MFS_MFSD6L	16..527	CDD:341032	121/607 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..237		7/25 (28%)