Protein Alignment jef and Mfsd6l

DIOPT Version :9

• Sequence 1: NP_001246323.1
• Gene: jef / 36634
• FlyBaseID: FBgn0033958
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_666116.1
• Gene: Mfsd6l / 215723
• MGIID: 2384904
• Length: 586
• Species: Mus musculus
• Alignment Length: 620
• Identity: 124/620 - (20%)
• Similarity: 214/620 - (34%)
• Gaps: 183/620 - (29%)

  Fly   132 PLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAPFWGSYADRCRQGKRLLLGSLACWVLFTIPLSF 196
            |.:.:|.:|:|:.....|||:|.:..:.....||....|.|.::.:..|.|||......::.:..
Mouse    32 PFLTLYLRQLGVAAPLVGILMGTKHLIATCWIPFCAFLAKRYQKRRMFLTGSLLSSAGASLLMVL 96

  Fly   197 IRPEAINCIERRNATDFVLTYTRTKRDLSAMYEQEHLDMG---TGTMPADEALEEAEAAHSRHKR 258
            :.|     ::|.....|....:|....:        |.:|   |..|...:.........|||.|
Mouse    97 VPP-----VDRNLVNHFCNGSSRVATTI--------LPLGVTQTVIMTPTQGSGAPNLPGSRHTR 148

  Fly   259 SL----------------------------------------------------------LLPRI 265
            :|                                                          |||..
Mouse   149 ALDTSGFPNGSEGTFSGLQTYLVGSVEGARTTTQGLHLVTSGLRDNSQKGTFEVGNVTLNLLPGS 213

  Fly   266 DAGISPVHINFVSNYDDKYHRDYVTPIFSSMVYRTPDIQKAFFLLLLVILIGEFFSAPAITLADS 330
            .|...||:::       |...|..||..||.  .:|   ..|.|.|.|::..|..:||...:||.
Mouse   214 TALGGPVNLS-------KPQGDTQTPDHSSK--GSP---WTFILSLGVVVFWELLAAPLEQVADD 266

  Fly   331 AVITLLGEDADKYGHQRMFGSLGW-----GISMFLVGIA--LDHSTSF--SNHPCGAGNKEKNYN 386
            ::...| :..|.....|..    |     |:|..:.|||  :.|....  :|.|.|.
Mouse   267 SLYEYL-DFVDATDRNRDL----WVWKLLGVSAGVCGIAALVGHLECLLVANGPQGV-------- 318

  Fly   387 ICFSIFSVLMTCAIISASKITFKYDPIDEQLAAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAV 451
            |.|..:|::.|.|:..::....   |||     |||.    |:.:|             :.:|::
Mouse   319 IYFYSYSLVSTLALAVSTAFPV---PID-----QQQG----PSYKA-------------IKALSL 358

  Fly   452 GSGSAASGACAGGVSSFLATGHQPQPHIGAESKVFAQTAKELPEWMTVLTHFKDLKTASFLFVAW 516
            ..|                                                  |.:.....|..:
Mouse   359 IRG--------------------------------------------------DSRLILLAFTVF 373

  Fly   517 FMGFGIGLIFTFLFWHLQDYGGTPTLFGVASVINHVSEIFAYFFSFRLITQIGHVKVLCLGLIGN 581
            ::|.....:..|||||::|:|.:..:.|.:..::.:.||..:.|...|:.::..|.||.|||...
Mouse   374 WIGATASTVQDFLFWHMKDHGSSELVMGFSVALSLLGEILFHPFRTSLLRKLSRVGVLGLGLGCL 438

  Fly   582 VLRFLYISYLTNPWMVLPFELMQGITHAAVWAASCSYIAHNTPKHLRASAQGVLQGIHHGLGRGC 646
            .|:.||.:::.:.|.|||.:::..|:..|:|.|..:.|.......:..|...:.:|..:|.|...
Mouse   439 ALQVLYYAFIWSWWSVLPVQILSTISSGALWWAVGASIEDLAFSGMERSLGTMFRGHFYGSGCSL 503

  Fly   647 GAIIGGMFVTYYGTTTTFRWYGIACLFVLGFFIFV 681
            |:.:||..|.::|....:....:..|..|..|:.:
Mouse   504 GSFVGGFVVLHFGIAVLYEACCVVLLLWLALFLSI 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jef	NP_001246323.1	MFS	125..187	CDD:304372	16/54 (30%)
		MFS	508..>681	CDD:119392	44/172 (26%)
		MFS_1	511..>701	CDD:284993	44/171 (26%)
Mfsd6l	NP_666116.1	MFS	<28..87	CDD:304372	16/54 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..237		7/25 (28%)
		MFS	365..>521	CDD:119392	41/155 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3762
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810