DRSC/TRiP Functional Genomics Resources

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Protein Alignment jef and LOC100493382

DIOPT Version :9

Sequence 1:NP_001246323.1 Gene:jef / 36634 FlyBaseID:FBgn0033958 Length:762 Species:Drosophila melanogaster
Sequence 2:XP_002934429.3 Gene:LOC100493382 / 100493382 -ID:- Length:2539 Species:Xenopus tropicalis


Alignment Length:348 Identity:64/348 - (18%)
Similarity:116/348 - (33%) Gaps:85/348 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 WVLFTI-PLSFIRPEAINCIERRNATDFVLTYTRTKRDLSAMYEQEH-----------LDMGTG- 238
            |.:..: |:..:.|.|.       |..:|.....|.:|.....|.|:           :|..|| 
 Frog    45 WTMDPLPPMGVVSPNAA-------AGTYVYKLQATDKDEGVSGEVEYFLLEGGDDRFAVDRSTGW 102

  Fly   239 -------TMPADEALEEAEAAHSRHKRSL-LLPRIDAGISPVHINFVS---NYDDKYHRDYVTPI 292
                   .:...|.|...:||....|:|. ::..:.||:.|......|   :..:.....||...
 Frog   103 IQTTGLPLLENKEYLLTVQAADMLGKKSAPIVVSVIAGLRPPQFKKASYSIHVPENVSPGYVLLT 167

  Fly   293 FSSMVYRTPDIQKAFFLLLLVILIGEFFSAPAITLADSAVITLLGEDADKYGHQRMFGSLGWGIS 357
            .|::.::...|..:     ||......||...:|   .||..:...|.::...:           
 Frog   168 VSALSHQNKSISYS-----LVRNPENLFSVHQLT---GAVTLIQSVDYEREPKE----------- 213

  Fly   358 MFLVGIALDHSTSFSN-----------HPC---------GAGNKEKNYNICFSIFSVLMT-CAII 401
            :.||..|::|....|:           :.|         ...|..:|..:..|:..|:.| |...
 Frog   214 LLLVVRAMEHLEQLSSTAEVHVFITDVNDCIPEFQQTIYSKDNVAENAAVMTSLLQVMATDCDSG 278

  Fly   402 SASKITFKYDPIDEQLAAQQQAQFVDPNKRAEEESMNQLAAQLNLPSLAVGSGSAASGACAGGVS 466
            ..|::::..:..|..::||   ..:.|.:..:.|....|   .....|||..|...        :
 Frog   279 FNSEVSYYTESADFSISAQ---GIISPVRALDYERPGHL---YEFVILAVDKGDKP--------N 329

  Fly   467 SFLATGHQPQPHIGAESKVFAQT 489
            :..||......::..|:..|:||
 Frog   330 TGTATVRIRISNVNDEAPEFSQT 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jefNP_001246323.1 MFS 125..187 CDD:304372 64/348 (18%)
MFS 508..>681 CDD:119392
MFS_1 511..>701 CDD:284993
LOC100493382XP_002934429.3 Cadherin_repeat 56..138 CDD:206637 17/88 (19%)
Cadherin_repeat 150..242 CDD:206637 18/110 (16%)
Cadherin_repeat 256..344 CDD:206637 19/101 (19%)
Cadherin_repeat 353..452 CDD:206637 64/348 (18%)
Cadherin_repeat 465..561 CDD:206637
Cadherin_repeat 570..658 CDD:206637
Cadherin_repeat 670..773 CDD:206637
Cadherin_repeat 781..888 CDD:206637
Cadherin_repeat 897..989 CDD:206637
Cadherin_repeat 998..1096 CDD:206637
Cadherin_repeat 1108..1203 CDD:206637
Cadherin_repeat 1216..1311 CDD:206637
Cadherin_repeat 1325..1417 CDD:206637
Cadherin_repeat 1425..1532 CDD:206637
Cadherin_repeat 1553..1625 CDD:206637
EGF_CA 1787..1822 CDD:238011
LamG 1826..2005 CDD:238058
LamG 2096..2217 CDD:214598
EGF 2247..2273 CDD:394967
EGF 2288..2319 CDD:214544
Cadherin_C 2379..2530 CDD:395833
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165175737
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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