Protein Alignment CG12866 and SLC16A7

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 116/591 - (19%)
• Similarity: 210/591 - (35%)
• Gaps: 181/591 - (30%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASV------------- 349
            |||||:||:::..:|::..........:.|....|.|....:.|.:::::|:
Human    13 PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGRIFE 77

  Fly   350 --------QIGCYFTS-----GAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFY 401
                    :|.|.||.     |..|:||:|::|.|.|.|||.|...:.::.:|:|.|:..|   |
Human    78 SFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQL---Y 139

  Fly   402 SVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNML 466
            ..:....|:.|:.....:..|:|.||.|.||||||.:.:|....:......|.:|....||:
Human   140 LTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWK--- 201

  Fly   467 RTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILS 531
                                                      |:|.:...|..:|..|.|
Human   202 ------------------------------------------GSFLILGSLLLNACVAGS----- 219

  Fly   532 TYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKEN 596
                                                 |:||          .||  .:.....:|
Human   220 -------------------------------------LMRP----------LGP--NQTTSKSKN 235

  Fly   597 VDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLK 661
            ..||          |:.          |..|.:|..  ::..|...|                 |
Human   236 KTGK----------TED----------DSSPKKIKT--KKSTWEKVN-----------------K 261

  Fly   662 LFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSS--ARTTIPVEY-ARMIGPIIGISNLVMRNIL 723
            ..|:.|.|...|.|.::...:..:||..|.::.:  |:.....|| |..:..::...::..|..:
Human   262 YLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSV 326

  Fly   724 GILAYKR--RSWTLGLCGCGLIFGGVSVLISAFYGE--NLIWFQFLYGFSY-AVAPAVYSTLRGL 783
            |::|..:  |..........::|.||..|:.....:  :|:.:...:|..: :|:..::.||..|
Human   327 GLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDL 391

  Fly   784 IYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLP 848
            :     |..:.::|.|:.::.......:|..:||||:.:||.|...:...| .::|:..:.||:.
Human   392 V-----GAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCG-AIVVAASVWLLIG 450

  Fly   849 LLIKCR 854
            ..|..|
Human   451 NAINYR 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	45/201 (22%)
		MFS	675..>839	CDD:119392	34/171 (20%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	114/589 (19%)
		MFS	20..449	CDD:119392	107/575 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850