Protein Alignment CG12866 and SLC16A5

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_005257847.1
• Gene: SLC16A5 / 9121
• HGNCID: 10926
• Length: 545
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 109/556 - (19%)
• Similarity: 201/556 - (36%)
• Gaps: 175/556 - (31%)

  Fly   300 DGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAVL 364
            ||.:.||:::.:.:.|.:..|....||:....:..:...|.|..|:..|:.......:|...::|
Human    49 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSIL 113

  Fly   365 INRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGIT-LSMIWA--SSQLIVGYY 426
            :.|||.|...:.|.:.:::.::|||:|.:|:.|.|      .||.|| |.|.::  ||..::|:|
Human   114 VGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYF------TAGFITGLGMCFSFQSSITVLGFY 172

  Fly   427 FERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQV 491
            |.|.|.:||..:..|...||.|:..|:.:|:..:|||       |..::
Human   173 FVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWR-------GTFLV---------------- 214

  Fly   492 GMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCP--------- 547
                            :|..::|..:    ..|..|.:.::..|..|:      ||
Human   215 ----------------FGGIFLHCCI----CGAIIRPVATSVAPETKE------CPPPPPETPAL 253

  Fly   548 SCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQ 612
            .|...|.|..::....|    ::|         ..||...|               ::|
Human   254 GCLAACGRTIQRHLAFD----ILR---------HNTGYCVY---------------ILG------ 284

  Fly   613 QVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILV 677
                                                      .|.:||
Human   285 ------------------------------------------VMWSVL----------------- 290

  Fly   678 ASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYK-----RRSWTLGL 737
              .|..|..|.:|:   :...::..:.|.::..|||.||:.:|.:.|::|.:     .|.:...|
Human   291 --GFPLPQVFLVPY---AMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSL 350

  Fly   738 CGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITS 802
               .|:..|::.|:.|..|:  .|....|..:|:|:.:....|...:.:..:.:.:...|.|:.:
Human   351 ---ALLLNGLTNLVCAASGD--FWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFT 410

  Fly   803 LAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLI 838
            :..|:...|...:||.|:..|.|:|..|..:...||
Human   411 VLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLI 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	47/178 (26%)
		MFS	675..>839	CDD:119392	38/169 (22%)
SLC16A5	XP_005257847.1	2A0113	41..493	CDD:273325	109/556 (20%)
		MFS	54..452	CDD:119392	107/551 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750