Protein Alignment CG12866 and SLC16A6

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_005257846.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 527
• Species: Homo sapiens
• Alignment Length: 585
• Identity: 117/585 - (20%)
• Similarity: 202/585 - (34%)
• Gaps: 147/585 - (25%)

  Fly   299 PDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFT---SGAF 360
            ||||:||.:.|..|..::...|:|.|.||....:....:.|.|.:|::.|:   |.|.   |...
Human    23 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISI---CVFVLTFSAPL 84

  Fly   361 SAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGY 425
            :.||.||||.|.|.:.|.|..:..::|:|:|..::.:   |..:....|:.....:..:..|:..
Human    85 ATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHM---YVAIGIISGLGYCFSFLPTVTILSQ 146

  Fly   426 YFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQ 490
            ||.:.|.:....:.:|....:..|......|...||||..| ...||:.|.:::..|.:.  |..
Human   147 YFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSL-LFVGLLQLNIVIFGALLR--PIF 208

  Fly   491 VGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWR 555
            :   ..|.|......|   |.....|:.::   .|:|:.:.:.:...:.....|..|:.:|.
Human   209 I---RGPASPKIVIQE---NRKEAQYMLEN---EKTRTSIDSIDSGVELTTSPKNVPTHTNL--- 261

  Fly   556 RRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKN 620
              :....||.|.:|::.:|         .|:|.:.|
Human   262 --ELEPKADMQQVLVKTSP---------RPSEKKAP----------------------------- 286

  Fly   621 IRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPM 685
                                                     |.|:.:||:..|...........:
Human   287 -----------------------------------------LLDFSILKEKSFICYALFGLFATL 310

  Fly   686 GFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGLCGCGLIFGG---- 746
            ||..|.:|     .||      :|..:||.......:|..:|...   ..|..|.|.:...
Human   311 GFFAPSLY-----IIP------LGISLGIDQDRAAFLLSTMAIAE---VFGRIGAGFVLNREPIR 361

  Fly   747 -----------VSVLISAFYGENLIW----FQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTN 796
                       ::|.:.||......|    ....:||........:..|  |.....:|:.|:::
Human   362 KIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPL--LAEDDVVGIEKMSS 424

  Fly   797 AFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAF--CFAGLCLIVSGFLKLLLPLLIKCRNRMAQ 859
            |.|:......:....|..:||.|:..:..||.||  |.||:.|..     :.|.|:..|:..:.|
Human   425 AAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAA-----VCLALVRPCKMGLCQ 484

  Fly   860  859
            Human   485  484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	45/178 (25%)
		MFS	675..>839	CDD:119392	38/184 (21%)
SLC16A6	XP_005257846.2	2A0113	23..512	CDD:273325	117/585 (20%)
		MFS	33..476	CDD:119392	109/565 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.840