Protein Alignment CG12866 and MCH5

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_014951.4
• Gene: MCH5 / 854483
• SGDID: S000005833
• Length: 521
• Species: Saccharomyces cerevisiae
• Alignment Length: 685
• Identity: 145/685 - (21%)
• Similarity: 209/685 - (30%)
• Gaps: 264/685 - (38%)

  Fly   214 PKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTA---------------SPESFSEYDGNRTRK 263
            |..| |||.....|.|..||    ..||...|.|:               ..||...:..|.:..
Yeast    24 PDLD-EDSIHYDPEADDLES----LETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSST 83

  Fly   264 QSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGF-GWVIMVLSFLAQLIIDGLIFTIGV 327
            ...|.|..:::|...|                   |:||| .||:....||..:...||:.:.||
Yeast    84 HDSDKEEDSNEEIESF-------------------PEGGFKAWVVTFGCFLGLIACFGLLNSTGV 129

  Fly   328 LLPSIAQDLDVSISSVS----------FVASVQI---GCYFTSGAFSAVLINRFGFRKVAIAGVL 379
             :.|..||..:|..|||          ||.|...   |.||          :|.|||.:.|.|.:
Yeast   130 -IESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYF----------DRNGFRTIMIVGTV 183

  Fly   380 CSAVSILASSWSVSLTMLIFFYSVLACAG-GITLSMIWASSQLIVGYYFERYRPMANGFSCSGGG 443
            .....:.|::.|......|..::::...| ||.||.:.:    :..:||.:.|..|...:..||.
Yeast   184 FHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVS----VPAHYFFKRRGTALAMATIGGS 244

  Fly   444 AGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYY 508
            .|.|:|        ||     |||:...:                          .|||  |..|
Yeast   245 VGGVVF--------PI-----MLRSFFSM--------------------------KSDT--DPTY 268

  Fly   509 GNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPA 573
            |..:....|....:...:.||:
Yeast   269 GFVWGIRTLGFLDLALLTLSII------------------------------------------- 290

  Fly   574 PLEREDLFYTGPAEYEKPHSKEN-VDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRER 637
             |.:|.|          ||..|| .||                                    |.
Yeast   291 -LVKERL----------PHVIENSKDG------------------------------------ES 308

  Fly   638 RWSNENQKKQNSCRNSRFMLTV--LKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTT- 699
            ||              |::|.|  |:.||.:.....::...|.......:..|....|..:..|
Yeast   309 RW--------------RYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATS 359

  Fly   700 --IPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGLCGCGLIFG----GVSVLISAFYGEN 758
              |....|..:..||.:..:..|.:.|.|:.|              ||    .::.|::.|....
Yeast   360 HGISANDAYTLIMIINVCGIPGRWVPGYLSDK--------------FGRFNVAIATLLTLFIVMF 410

  Fly   759 LIWFQF------------LYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFG----ITSLAMGM 807
            :.|..|            ||||   .:.:|:|    |:.|....:|| |..||    .....:|.
Yeast   411 VGWLPFGTNLTNMYVISALYGF---CSGSVFS----LLPVCCGQISK-TEEFGKRYSTMYFVVGF 467

  Fly   808 GAFIGTTIAGKLIGI--TGNYSAAFCFAGLCLIVS 840
            |..:|..|.|.:|.|  |.:|.....|.||...||
Yeast   468 GTLVGIPITGAIISIKTTADYQHYIIFCGLATFVS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	47/189 (25%)
		MFS	675..>839	CDD:119392	43/188 (23%)
MCH5	NP_014951.4	MFS_MCT_SLC16	106..510	CDD:340910	121/579 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840