Protein Alignment CG12866 and slc16a5b

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_001919658.1
• Gene: slc16a5b / 794371
• ZFINID: ZDB-GENE-131120-181
• Length: 547
• Species: Danio rerio
• Alignment Length: 642
• Identity: 125/642 - (19%)
• Similarity: 218/642 - (33%)
• Gaps: 203/642 - (31%)

  Fly   240 TTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDF------SRGGRRLGSGMVFIYMVIP 298
            |||..:..:|.::|...|....:.:..|.|.:..:.|...      |.||:....        :.
Zfish    14 TTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQ--------LA 70

  Fly   299 PDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAV 363
            ||||:|||::..:.|...:.......||:....:..|...|.:..|:|.::.:......|...:|
Zfish    71 PDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNTETSWVPAIMMAVLHACGPICSV 135

  Fly   364 LINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFE 428
            |:.|.|.|...|.|.:.|.:.:.|||::.::..|   |.......|:..|:.:..|..:||:||.
Zfish   136 LVERCGCRATIIIGGILSGLGMAASSFAQTMVEL---YITAGIITGMGFSLCFQPSITMVGHYFV 197

  Fly   429 RYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGM 493
            |.|..||..|.:|...|:.:...|.::|:...|||.......|:::
Zfish   198 RRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLL------------------- 243

  Fly   494 YHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRK 558
                                                                     |||
Zfish   244 ---------------------------------------------------------NCC----- 246

  Fly   559 KSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRV 623
                  ....::|  ||..:....|...|.:..|.|              .|...|:.|:|.
Zfish   247 ------VCGAVMR--PLAAKPKTETRTKETDNHHLK--------------TNCLSVHQGLKG--- 286

  Fly   624 DDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFL------ 682
                                        ..|..|:.:..|   |.:...|.:|.::.:.
Zfish   287 ----------------------------RLRATLSTIMTF---LRRHMAFDLLCSNPYFCAYALG 320

  Fly   683 ---FPMGFNIPFVYSSARTT---IPVEYARMIGPIIGISNLVMRNILGI---LAYKRRSWT---- 734
               ..:||.:|.||.....|   :..:.|.::..|:|:.|:::|....|   |...|.|..
Zfish   321 VSWMMLGFVVPLVYLVPYATAYGMEQDQAALLMAILGLINIIVRPATAIVFGLPRFRGSHNFAYL 385

  Fly   735 ---------LGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLG 790
                     |..|.||:   |.|.|:       |:.:..|:|||.::..::..|    :.:..:.
Zfish   386 FAIAVVINGLSNCVCGI---GTSFLV-------LLVYVILFGFSMSLVGSLLFT----VLMDTVE 436

  Fly   791 LSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAF--C-----FAGLCLIVS 840
            :|:..:|.|:.|:...:...:|..:||.|:..||.|...|  |     .|||.:::|
Zfish   437 MSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	41/175 (23%)
		MFS	675..>839	CDD:119392	45/198 (23%)
slc16a5b	XP_001919658.1	2A0111	71..511	CDD:331689	113/577 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850