Protein Alignment CG12866 and SLC16A2

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 106/580 - (18%)
• Similarity: 189/580 - (32%)
• Gaps: 200/580 - (34%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSF----VASVQIGCYFTSG 358
            ||:||||||::..:......|.|:..::|:|...:.::.......|.|    |.::.:|..|...
Human    94 PPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCS 158

  Fly   359 AFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIV 423
            ...::..:|.|.|..|.||...:.:.:..||::.||::..|.|.:|.   |...|..:..|.:|:
Human   159 PIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILF---GCGCSFAFQPSLVIL 220

  Fly   424 GYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAP 488
            |:||:|...:|||...:|.....:.|.||...|...|......:..:..:.:::|:.:.|..:
Human   221 GHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPL-- 283

  Fly   489 TQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCC 553
                   ||.|.||                                  |.|:|
Human   284 -------LPSSQDT----------------------------------PSKRG------------ 295

  Fly   554 WRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGI 618
                                                                             
Human   296 ----------------------------------------------------------------- 295

  Fly   619 KNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLF 683
                       :..:|:                  ||:..:.|.|:.|:.:|..::|........
Human   296 -----------VRTLHQ------------------RFLAQLRKYFNMRVFRQRTYRIWAFGIAAA 331

  Fly   684 PMGFNIPFVYSSARTTIPVEYARM---------IGPIIGISNLVMRNI--------------LGI 725
            .:|:.:|:|:  ....:..|::.:         ||...|:..||..:|              |..
Human   332 ALGYFVPYVH--LMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSF 394

  Fly   726 LAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLG 790
            |.....|..:.||   ..|||: :::..|.|               :....:.|:...|..:.:|
Human   395 LLLGLMSMMIPLC---RDFGGL-IVVCLFLG---------------LCDGFFITIMAPIAFELVG 440

  Fly   791 LSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLL 850
            ..:.:.|.|.....|.:....|..|||.|....|:|..||.|||:..|:...:...:||:
Human   441 PMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLM 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	40/179 (22%)
		MFS	675..>839	CDD:119392	39/186 (21%)
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92
		2A0113	86..513	CDD:273325	106/580 (18%)
		MFS	101..498	CDD:119392	98/569 (17%)
		DUF1564	<286..>334	CDD:284922	14/187 (7%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750