Protein Alignment CG12866 and SLC16A12

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_998771.3
• Gene: SLC16A12 / 387700
• HGNCID: 23094
• Length: 516
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 104/574 - (18%)
• Similarity: 188/574 - (32%)
• Gaps: 177/574 - (30%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCY-FTSGAFS 361
            |||||:||:|:...||..:....:...|.:.............:..:::.|: :.|. .......
Human    42 PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSI-VDCVTMLCAPLG 105

  Fly   362 AVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYY 426
            :|:.|....:...:.|.|.::..::.||::.||..|   |..|....|:..::.::.:..:||.|
Human   106 SVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHL---YLTLGVLTGLGFALCYSPAIAMVGKY 167

  Fly   427 FERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQV 491
            |.|.:.:|.|.:.||.|.|..:...:...|:....||..|....|.::
Human   168 FSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVL----------------- 215

  Fly   492 GMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRR 556
                                                                       |.|
Human   216 -----------------------------------------------------------NLC--- 218

  Fly   557 RKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNI 621
                    ....|:||..|:                              .|..|.:.|:..:..
Human   219 --------VCGALMRPITLK------------------------------EDHTTPEQNHVCRTQ 245

  Fly   622 RVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMG 686
            :.|        :.|...:|:..::...:|      |......:|..|...:|.:|..|......|
Human   246 KED--------IKRVSPYSSLTKEWAQTC------LCCCLQQEYSFLLMSDFVVLAVSVLFMAYG 296

  Fly   687 FNIPFVYSSARTTIPVEYARMIG----------PIIGISNLVMRNILGILAYKR---------RS 732
            .:..|||.       |.||..:|          .|:|:.:::.....|.|..:|         ..
Human   297 CSPLFVYL-------VPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYL 354

  Fly   733 WTLGLCG-CGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTN 796
            :.:|:.| |.|....:..|      ..|:.|...:|:    ....|.||..::..:.:|.:.|::
Human   355 FAVGMDGLCYLCLPMLQSL------PLLVPFSCTFGY----FDGAYVTLIPVVTTEIVGTTSLSS 409

  Fly   797 AFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVS----GFLKLL 846
            |.|:......:...:...|||:|:..||:|:|||...|..:|.|    ||.:|:
Human   410 ALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	33/176 (19%)
		MFS	675..>839	CDD:119392	41/183 (22%)
SLC16A12	NP_998771.3	2A0111	42..481	CDD:331689	104/574 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750