Protein Alignment CG12866 and chk

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Alignment Length: 845
• Identity: 166/845 - (19%)
• Similarity: 292/845 - (34%)
• Gaps: 277/845 - (32%)

  Fly   238 NVTTVQLADTAS-----PESFSEY-DGNRT-----------RKQSFDMESKNSKESFDFSRGGRR 285
            |::..:|||.|.     ..|..|. ||..|           ||:....||.:|.:|....:...:
  Fly    67 NLSVEELADGAGHSRVVRSSVIELEDGTMTCLMNGNGQVKRRKRLISNESGDSIDSSSTEKKTPK 131

  Fly   286 LGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQ 350
            :            ||||:|||::..|.:..||.|||.|:.|::...:.:....|.|..::::|:.
  Fly   132 M------------PDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLF 184

  Fly   351 IGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMI 415
            .......|...:.|::::|.||:.|.|.:.||.....||:..|:.||:..:.:::   |:.|.:.
  Fly   185 FSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIIS---GLGLGIG 246

  Fly   416 WASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWR----------------- 463
            :.::.:.:.::|::.|..|.|...||.|.|..::..|.|:|:...|||
  Fly   247 YVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCG 311

  Fly   464 ------------NMLRTQAGLIMLILLMVVAYVEV-------APTQVGMYHLPGSSDTSSDEYYG 509
                        |.|.:::..:.......|...|:       ...:..:..|...::|.:
  Fly   312 ALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEA----- 371

  Fly   510 NFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLL----- 569
            |..:.|.|..:....:|...|.|:....:.....: ..|.|....|.::..:....:|||
  Fly   372 NQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICE-VKSLSRRSLRHKEGEEAPSRENLLSMSSG 435

  Fly   570 ---------------------IRPAPLEREDLFYTGPAEYEKPHSKENV----DGKEFLLMGSDK 609
                                 |.....|.....|....|...|..|.:.    :|.   |..||:
  Fly   436 AGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGS---LRSSDE 497

  Fly   610 N--TQQ-----------------VNYGIKNIRVDD--------------------------EPDR 629
            .  ||:                 ....|.|::|:.                          ||.|
  Fly   498 GYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSR 562

  Fly   630 --------------------------------ISRVHRERRWSN--ENQKKQNSCRNSRF----- 655
                                            |.|:.|.::.|:  .|.::..|.|||.|
  Fly   563 RIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMR 627

  Fly   656 --------------------------------MLTVLK----------------LFDYRLLKQFE 672
                                            |.|:.|                :||:.|....:
  Fly   628 IHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMK 692

  Fly   673 FKIL-VASAFLFPMGFNIPFVY-------------SSARTTIPVEYARMIGPIIGISNLVMRNIL 723
            |.:. :::.||| :.|.||::|             .||.....|..|:.:| :||:      ..|
  Fly   693 FALFNLSTLFLF-IWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVG-MIGL------GYL 749

  Fly   724 GILAYKR----RSWTLGLCGCGLIFGGVSVLISAFYGENL--IWFQFLYGFSYAVAPAVYSTLRG 782
            |.|::..    .|..:.:||..:.|  :.:||:.:.|..:  :.|.|.:..|::..|:
  Fly   750 GDLSWMNINICYSLCMLVCGASVFF--MPLLITNYMGLMVMCVIFGFTFASSFSFTPS------- 805

  Fly   783 LIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLL 847
             |.|..:.|...|.|:|:..|..|:|...|..|||.:...||.:...|.:||:.:.:||....|:
  Fly   806 -ILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLI 869

  Fly   848  847
              Fly   870  869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	44/204 (22%)
		MFS	675..>839	CDD:119392	46/183 (25%)
chk	NP_001163063.1	MFS	143..>315	CDD:119392	41/174 (24%)
		MFS	<685..869	CDD:119392	50/201 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910