DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12866 and out

DIOPT Version :9

Sequence 1:	NP_001286425.1	Gene:	CG12866 / 36630	FlyBaseID:	FBgn0033955	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001285435.1	Gene:	out / 32926	FlyBaseID:	FBgn0259834	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	624	Identity:	130/624 - (20%)
Similarity:	217/624 - (34%)	Gaps:	158/624 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 IPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFS 361
            :.||||:|||:.:.:.|....:...:...|::.....|.|.......:.:.:|.:......|..:
  Fly    37 VAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVN 101

  Fly   362 AVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAG---GITLSMIWASSQLIV 423
            ..:..||.||:||:.|...:.:.:..|::..:      |:..:.|..   ||.|.:..|::.|.|
  Fly   102 GAMFRRFTFRQVALTGTSLAFLGVFLSAFCTT------FWQYIICLSAIFGIGLGLAMAATSLAV 160

  Fly   424 GYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAP 488
            ..||:..|..|.|||.:..|.|.:.|..:::.|:...|.:..:...||:.|..:|..:....|
  Fly   161 NTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPV-- 223

  Fly   489 TQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPS----- 548
                ::|:......          ||:.:...|.|.|       .:|...:.......||
  Fly   224 ----LWHVKKPEKP----------VHNTIEGIAETEK-------LQPELLEANGNLLSPSNDPWK 267

  Fly   549 ---CSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLM----- 605
               |..|.:::|.|......|.|.....| ||.....|.|.......:.:...|.:..|.
  Fly   268 DYECKYCQYQKRSKRGLFSSQYLFNVDDP-ERPGYEITEPGTPMLARANDGWFGSKLSLTSESAG 331

  Fly   606 GSDKNTQQV------NYGIKNI------RVDDEPDRISRV--------HRERR-----------W 639
            |:...|:|.      :...:|:      |.|..||..|..        :|||.           :
  Fly   332 GARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVY 396

  Fly   640 SNENQKKQNSC-----------------------------------RNSRFMLTVLKLFDYRLLK 669
            |...|.:...|                                   |...|...|.|.||..||:
  Fly   397 SRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLR 461

  Fly   670 QFEFKILVA--SAFLF-PMGFNI--PFV-----YSSARTTIPVEY-------ARMIGPI----IG 713
            .|.|..|..  |..:| .|.|::  ||:     |:..:.::.:..       .|.:.|:    :.
  Fly   462 DFTFVNLAVGMSIMMFGEMNFSVLTPFILNSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVK 526

  Fly   714 ISNLVMRNILGILAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYS 778
            :.|.|: ...|||.              :..|.|.|..:..| |.:|....|.||..|.. .::|
  Fly   527 LDNRVL-FAFGILC--------------IAVGRVVVAFTDSY-EIMIGVFLLIGFGKAFR-TIFS 574

  Fly   779 TLRGLIYVKYLGLSKLTNAFGI-----TSLAMGMGAFIG 812
            .   ||...|:.|::|..|.|:     |..:..||..:|
  Fly   575 P---LIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILG 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	38/178 (21%)
CG12866	NP_001286425.1	MFS	675..>839	CDD:119392	37/164 (23%)
out	NP_001285435.1	MFS	45..>225	CDD:119392	41/191 (21%)
		MFS	<464..621	CDD:119392	38/167 (23%)
		MFS_1	468..>621	CDD:284993	37/163 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446228
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850