Protein Alignment CG12866 and Slc16a12

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001178566.1
• Gene: Slc16a12 / 309525
• RGDID: 1311468
• Length: 486
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 120/603 - (19%)
• Similarity: 198/603 - (32%)
• Gaps: 197/603 - (32%)

  Fly   285 RLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPS----IAQDLDVSISSVSF 345
            |:||..       |||||:||:|:...||..:....:...|.:....    .|||    .|..::
  Rat     6 RVGSAS-------PPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQD----YSQTAW 59

  Fly   346 VASVQIGCY-FTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGG 409
            :.|: :.|. .......:|:.|:...:...:.|.|.::..::..|::.||..|.....||.   |
  Rat    60 IHSI-VDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLT---G 120

  Fly   410 ITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIM 474
            :..::.::.:..:||.||.|.:..|.|.:.||.|.|..:...:...|:....||..|....|
  Rat   121 LGFALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGG--- 182

  Fly   475 LILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKK 539
            .:|.:.|....:.|  :.:...|...:.|.|        .|..|:....|      |.|.|..|:
  Rat   183 FVLNLCVCGALMRP--ITLKEDPSGPEKSHD--------RDAQREDCKQA------SPYSPLTKE 231

  Fly   540 KGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLL 604
            ....:.|  ||                        |::                     |..|||
  Rat   232 WTETRLC--CS------------------------LQQ---------------------GYGFLL 249

  Fly   605 MGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLK 669
            |.
  Rat   250 MS--------------------------------------------------------------- 251

  Fly   670 QFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIG----------PIIGISNLVMRNILG 724
              :|.:|..|......|.:..|||.       |.||..:|          .|:|:.::|.....|
  Rat   252 --DFVVLAVSVLFMAYGCSPLFVYL-------VPYALSVGVSHHQAAFLMSILGVIDIVGNITFG 307

  Fly   725 ILA-------YKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFS--YAVAPAVYSTL 780
            .|.       |:...:...:...||.:..:.:|.|         |..|..||  :......|.||
  Rat   308 WLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQS---------FPLLVPFSCTFGYFDGAYVTL 363

  Fly   781 RGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVS----G 841
            ..::..:.:|.:.|::|.|:......:...:...|||.|:..||:|:|||...|..:|.|    |
  Rat   364 IPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLG 428

  Fly   842 FLKLL-------LPLLIK 852
            |.|:.       :|.|:|
  Rat   429 FAKIAKRMKRTQVPFLVK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	38/180 (21%)
		MFS	675..>839	CDD:119392	42/182 (23%)
Slc16a12	NP_001178566.1	2A0111	12..451	CDD:331689	117/590 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..221		5/27 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339255
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750