Protein Alignment CG12866 and Slc16a2

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_671749.2
• Gene: Slc16a2 / 259248
• RGDID: 628608
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 106/585 - (18%)
• Similarity: 184/585 - (31%)
• Gaps: 210/585 - (35%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSF----VASVQIGCYFTSG 358
            ||:|||||:::..:......|.|:..::|:|...:.::.......|.|    |.::.:|..|...
  Rat   100 PPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCS 164

  Fly   359 AFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIV 423
            ...::..:|.|.|..|..|...:.:.:..||::.||::..|.|.:|.   |...|..:..|.:|:
  Rat   165 PIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILF---GCGCSFAFQPSLVIL 226

  Fly   424 GYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAP 488
            |:||:|...:|||...:|.....:.|.||...|...|......:..:..:.::.|:.:.|..:
  Rat   227 GHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPL-- 289

  Fly   489 TQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCC 553
                   ||.|.||                                  |.|:|
  Rat   290 -------LPSSQDT----------------------------------PSKRG------------ 301

  Fly   554 WRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGI 618
                                                                             
  Rat   302 ----------------------------------------------------------------- 301

  Fly   619 KNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLF 683
                          .|..|:               ||::...|.|:.|:.:|..::|........
  Rat   302 --------------AHTLRQ---------------RFLVQFRKYFNMRVFRQRTYRIWAFGIAAA 337

  Fly   684 PMGFNIPFVYSSARTTIPVEYAR--------------MIGPIIGISNLVMRNI------------ 722
            .:|:.:|:|:.       ::|..              .||...|:..||..:|
  Rat   338 ALGYFVPYVHL-------MKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYL 395

  Fly   723 --LGILAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIY 785
              |..|.....|..:.||   ..|||: :::..|.|               :....:.|:...|.
  Rat   396 QVLSFLLLGLMSMMIPLC---RDFGGL-IVVCLFLG---------------LCDGFFITIMAPIA 441

  Fly   786 VKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLL 850
            .:.:|..:.:.|.|.....|.:....|..|||.|....|||..||.|||:..|:...:...:||:
  Rat   442 FELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVAFYFAGVPPIIGAVILFFVPLM 506

  Fly   851  850
              Rat   507  506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	39/179 (22%)
		MFS	675..>839	CDD:119392	40/191 (21%)
Slc16a2	NP_671749.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..98
		2 X 22 AA approximate tandem repeats	29..72
		Trypan_PARP	<65..104	CDD:424334	2/3 (67%)
		MFS_MCT8_10	106..504	CDD:340978	99/575 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..545

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840