Protein Alignment Targ and Slc16a4

DIOPT Version :10

• Sequence 1: NP_001286425.1
• Gene: Targ / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_666248.1
• Gene: Slc16a4 / 229699
• MGIID: 2385183
• Length: 500
• Species: Mus musculus
• Alignment Length: 578
• Identity: 110/578 - (19%)
• Similarity: 213/578 - (36%)
• Gaps: 116/578 - (20%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSA 362
            |.|||:||::::..||..:.:.|:..|..:......::.:.:...:.::.|:.....|::|..:|
Mouse    14 PLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAA 78

  Fly   363 VLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYF 427
            ::.:..|.:..:|.|....:...:.|||:..:..|.....:|.   |:..:.::..:.:::..||
Mouse    79 IICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLP---GLGSAFLYQVAAVVITKYF 140

  Fly   428 ERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVG 492
            ::...::...:.||.|...:|..| ..:|:.:..|...|          :|.....:.:.|:.:.
Mouse   141 KKRLGLSTAIARSGMGLTFLLAPF-TKFLIDLYDWTGAL----------ILFGAIILNLVPSSML 194

  Fly   493 MYHLPGSSDTSSD-EYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRR 556
            :..:...|:.:|| |..|                  ||||..||.      |.:....|.|
Mouse   195 LRPIHSQSNNNSDIENKG------------------SILSATEPE------ASYKTETSKC---- 231

  Fly   557 RKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNI 621
                  .:.|...|:.:.:::.          |:|.:...|.|.:
Mouse   232 ------KETQEPFIKDSTMKKS----------EQPTTTLTVLGNQ-------------------- 260

  Fly   622 RVDDEPDRISRVHRERRWSNENQKKQN------SCRNSRFMLTVLKLFDYRLLKQFEFKILVASA 680
                ..:..:|.||.|.....|.|...      :|:.        ||.|..|.:...|.|...|.
Mouse   261 ----SEEFSNRPHRNRPLLMSNGKSHKKKFVSWNCKQ--------KLLDISLFRNPFFYIFTWSF 313

  Fly   681 FLFPMGFNIPFVYSSARTT---IPVEYARMIGPIIGISNLVMRNILGILA-------YKRRSWTL 735
            .|..:.:.||..:..||..   |.|..|..:..:.||:..|.:.|.|.:|       |:.....|
Mouse   314 LLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKSYL 378

  Fly   736 GLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGI 800
            .|||...:...::..........:::..|..|:...:.|.:....:.....|:||.:
Mouse   379 ILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVDLSKNSRVHKFLGYA-------- 435

  Fly   801 TSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMA 858
             |...|:....|..|||.:...|..|:.:|.|:|.|.|:|......:||..:.:.:.:
Mouse   436 -SFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKRKQS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Targ	NP_001286425.1	MFS_MCT_SLC16	304..842	CDD:340910	104/554 (19%)
Slc16a4	NP_666248.1	MFS_MCT5	20..486	CDD:340979	106/564 (19%)