Protein Alignment CG12866 and SLC16A13

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_963860.1
• Gene: SLC16A13 / 201232
• HGNCID: 31037
• Length: 426
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 119/568 - (20%)
• Similarity: 188/568 - (33%)
• Gaps: 199/568 - (35%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSA 362
            |||||:|||:::.:|....::.|::.:.||.........:...:.||::||:.|..........:
Human     7 PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPVGS 71

  Fly   363 VLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYF 427
            .|..:||.|.|.:.|.:.:|:.:|.:|::.|||.|.....:|:.:|   .::.:|.:...:..||
Human    72 ALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSG---WALTFAPTLACLSCYF 133

  Fly   428 ERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVG 492
            .|.|.:|.|.:.:|.|.....|.....||:....||..|.    |:..:.|.:||
Human   134 SRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLL----LVSALSLHLVA---------- 184

  Fly   493 MYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRR 557
                                                                        |
Human   185 ------------------------------------------------------------C---- 185

  Fly   558 KKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIR 622
                     ..|:|| |...||....||
Human   186 ---------GALLRP-PSLAEDPAVGGP------------------------------------- 203

  Fly   623 VDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGF 687
                                           |..||       .||....|.....:..|...|:
Human   204 -------------------------------RAQLT-------SLLHHGPFLRYTVALTLINTGY 230

  Fly   688 NIPFVYSSAR------TTIPVEYARMIGPIIGISNLVMRNILGIL--------AYKRRSWTLGLC 738
            .||:::..|.      ..:|   |..:..::.||:||.|.:.|.|        ......||. |.
Human   231 FIPYLHLVAHLQDLDWDPLP---AAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTT-LT 291

  Fly   739 GCGLIFGGVSVLISAFYGENLIWFQFLYGF-SYAVAPAVYSTLRGLIYVK--YLGLSKLTNAFGI 800
            |..|....|:...:|     |:.....||| |.|:||..:|.|..||..:  |.||       |:
Human   292 GVSLALFPVAQAPTA-----LVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGL-------GL 344

  Fly   801 TSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLP 848
            ..:...:|..:|..::|.|..:||||:|:|..||..|:....:.|.||
Human   345 LQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	43/175 (25%)
		MFS	675..>839	CDD:119392	50/180 (28%)
SLC16A13	NP_963860.1	MFS	14..392	CDD:119392	111/559 (20%)
		MFS_1	21..357	CDD:284993	96/517 (19%)
		DUF3172	369..>419	CDD:288260	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850