Protein Alignment Targ and mct-5

DIOPT Version :10

• Sequence 1: NP_001286425.1
• Gene: Targ / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_495464.2
• Gene: mct-5 / 187995
• WormBaseID: WBGene00020168
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 155/605 - (25%)
• Similarity: 265/605 - (43%)
• Gaps: 97/605 - (16%)

  Fly   297 IPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFS 361
            :|||||:|||:::.||...:..||.:::.|:|...:..:.:.:.:..|.:.|:..|....:|..:
 Worm    13 LPPDGGWGWVVVIGSFFIHVFADGFVYSFGILAEKLMIEFNSNNTMTSLIVSMLTGFTLGAGPLA 77

  Fly   362 AVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYY 426
            :.:.|::|.|...|.|...:.|..|.|.::..:...:....|:.   ||...:::..:.:||..|
 Worm    78 SAVCNKYGCRITTIIGAGVAFVGCLLSCFATEIWHFVISVGVIM---GIGFGLVYCPAIVIVTMY 139

  Fly   427 FERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQV 491
            ||..|.:|.|.:.:|.|.|.|:|..:|::::...|||.:.   ...:.:|:|..|......|.|.
 Worm   140 FESKRSLATGIAVAGAGVGAVVFGPINTFIISNYGWRYVF---VLFLFVIILCAVCGATFVPLQF 201

  Fly   492 GMYHLPGSSDTSSDEYYGNFYVH-----DYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSN 551
            .:  :|   |...|..|.:.:..     ||.::   ..:..|:||  .|:..::..::.|....|
 Worm   202 AL--VP---DDDDDGEYNDVFEDEVKKIDYNKR---FEEKVSLLS--PPQVLERSMSQCCDIQKN 256

  Fly   552 CCWRRRKKSQNADEQNLLIRP----------APLEREDLFYTG-----------PAEYEKP---H 592
            ....|...|..|.:...|:||          ..|.|:|:||||           |.:|...   |
 Worm   257 NQHARPSSSVGAVDLEPLLRPRCGTIGERNSGYLNRKDVFYTGSISNVAEFRANPDKYRSTGSLH 321

  Fly   593 SKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQ----NSCRNS 653
            :..|:.......:|.|:.:   .:|     .|...|.:            |:||:    :....|
 Worm   322 TALNIHTHHTGTVGDDRES---GHG-----CDQSLDGM------------NEKKETDFMDDIEGS 366

  Fly   654 RFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPII---GIS 715
            ....|:..:|.::||....|.:...|..|..:|||.|..:.....|..:....:.|.|:   |.:
 Worm   367 NMFKTINNMFSFQLLLDPAFLLFAISNLLTSVGFNSPLYFLPLHVTNILSDNNVSGNILSVYGTA 431

  Fly   716 NLVMRNILGILA--------------YKRRSW--TLGLCGCGLIFGGVSVLISAFYGENLI-WFQ 763
            |.:.|.|.|::|              .:.|.|  .:.|..||:    |:.....|.|..|: .:.
 Worm   432 NTIGRLIFGVVADQKLPLPAGLGDDTARNRLWMYNISLTICGI----VTAFCYKFDGYILLDIYA 492

  Fly   764 FLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSA 828
            .|:||:.    |.|..|..:|.|..|||.|||||||:..|..|:|..||..::|.|..:||||:.
 Worm   493 VLFGFTI----ASYVCLTSVILVDLLGLDKLTNAFGLLLLWQGVGTVIGPLVSGYLADLTGNYTL 553

  Fly   829 AFCFAGLCLIVSGFLKLLLP 848
            :|.|.|:.|:|||.:..::|
 Worm   554 SFVFCGINLMVSGLMLFVIP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Targ	NP_001286425.1	MFS_MCT_SLC16	304..842	CDD:340910	148/590 (25%)
mct-5	NP_495464.2	MFS_MCT_SLC16	20..573	CDD:340910	149/596 (25%)