Protein Alignment Targ and mct-2

DIOPT Version :10

• Sequence 1: NP_001286425.1
• Gene: Targ / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_503681.2
• Gene: mct-2 / 182056
• WormBaseID: WBGene00015273
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 572
• Identity: 146/572 - (25%)
• Similarity: 243/572 - (42%)
• Gaps: 104/572 - (18%)

  Fly   296 VIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAF 360
            |.|||||:|||::..|||..:.:||:|:|.|.:|..|..|...|.|....|.|:..|||:.:|..
 Worm    37 VTPPDGGYGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQFGSTSVAGAVISILTGCYYLAGPL 101

  Fly   361 SAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGY 425
            ::..:|.||.|.|||||.:.:..:.|.|.::.::..|...:.||   |||....::..|.:|:..
 Worm   102 ASSFVNVFGIRSVAIAGSILATTAFLLSRFASTIWELYLLFGVL---GGIGFGCMYLPSIVILST 163

  Fly   426 YFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQ 490
            ||.:.|.:|.|.:..|.|.|.::|:.:|..:....|      ...|..|:.|    |.:.::.:.
 Worm   164 YFAKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFG------KDVGSFMVYL----AAIAISGSL 218

  Fly   491 VGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWR 555
            ..:...|    ..:.|:              ...|...::..||.:|::       |:
 Worm   219 FSLLFAP----LKATEH--------------QVKKVAKMVRNYEGKPEE-------PT------- 251

  Fly   556 RRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHS-----KENVDGKEFLLMGSDKNTQQVN 615
            :|......::...|.||.  ...|.||.|.|...:..|     |.....:..::..::.:|
 Worm   252 QRLLEDVRNDLEELNRPG--HNADTFYAGNAPVSRSRSNTLDRKAAESAEAHVVHATEHHT---- 310

  Fly   616 YGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASA 680
                             ||...:.|...:.|::.|          .:.|..||....|..|..|.
 Worm   311 -----------------VHHVVKKSKFTKFKESLC----------SVLDKDLLFSPSFMTLAVSG 348

  Fly   681 FLFPMGFNIPFVY------------SSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSW 733
            ....:.|.:||||            :.|..::||       .:||..|::.|...|::|...:..
 Worm   349 TFTVLSFLVPFVYLALAMKQKNPDFTDAELSLPV-------TLIGAFNIMFRIGCGMVADHPKMS 406

  Fly   734 TLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAF 798
            .|.:.....|..|.|:|...|..|  :|...::...::...|.::.||.:|.|:.:|:.||:|||
 Worm   407 ALQVSNVATIIAGTSMLFVPFCTE--LWHYVVFCIPFSAGVACFAALRSVICVELIGVEKLSNAF 469

  Fly   799 GITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLL 850
            ||..:.||:||.:|..||.::..|||||..:|...|:....||.:.:.||.|
 Worm   470 GILMVFMGIGAVVGGPIAAQIKDITGNYDISFYVMGIIFAFSGVMTIRLPEL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Targ	NP_001286425.1	MFS_MCT_SLC16	304..842	CDD:340910	136/554 (25%)
mct-2	NP_503681.2	MFS_MCT_SLC16	45..519	CDD:340910	137/560 (24%)