Protein Alignment CG12866 and mct-6

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_510705.1
• Gene: mct-6 / 181724
• WormBaseID: WBGene00015676
• Length: 594
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 160/643 - (24%)
• Similarity: 267/643 - (41%)
• Gaps: 136/643 - (21%)

  Fly   280 SRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVS 344
            |.||.:|        :.:|||||:|||:::.||...:..||.:::.|||:.::.::...|.:..:
 Worm     7 SSGGGKL--------VPLPPDGGWGWVVVLGSFFVHVFADGFVYSFGVLVETLMEEFHASNTMAA 63

  Fly   345 FVASVQIGCYFTSGAFSAVLINRFGFRKVAIAG-----VLCSAVSILASSWSVSLTMLIFFYSVL 404
            .:.|:..|....||..::.:.|::|.|...|.|     |.|:......:.|.:.:|:.:..
 Worm    64 LIISLLTGLTLGSGPLASAVCNKYGCRITTITGAGVAFVGCALSYFATAMWHIVITVGVIM---- 124

  Fly   405 ACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQ 469
                |....:::..:.:||..|||..|.:|.|.:.:|.|.|.|||..:|::.:...|||::.
 Worm   125 ----GTGFGLMYCPAIVIVTMYFENKRSLATGIAVAGAGVGTVLFAPINAFFINNYGWRSVF--- 182

  Fly   470 AGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYE 534
            ...:.:::|..:.....||.:..:  :|...:..:||     .:.:.::::|...:.....:...
 Worm   183 LAFLFILVLCALCGATFAPLEFAL--VPDEEEEVNDE-----VLDEDVKKTAANEEHGEKATLLS 240

  Fly   535 PRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAP------------------------- 574
            |           ||.......:....|.|.|:   ||||.
 Worm   241 P-----------PSLLERSMSQSSGVQKAGEK---IRPASSMGAVDVESQPRSRRGTVGERDSGY 291

  Fly   575 LEREDLFYTGP----AEYEKPHSKENVDGKEFLLMGSDKNTQQV---NYGIKNIRVDDEPDRISR 632
            |.|:|:||||.    ||:.:...|....|.   |.|.......:   :.|    |:||
 Worm   292 LNRKDVFYTGSISNVAEFREDPDKYRSTGS---LHGRHTTVGSIPAHSTG----RLDD------- 342

  Fly   633 VHRERRWSNENQK------KQNSCRNS------RFMLTVLKLFDYRLLKQFEFKILVASAFLFPM 685
               .|..|.|:.|      |.|...|:      ....|:..:....||.:..|.:...|..|..:
 Worm   343 ---VREGSEEDSKAMDISEKTNGTDNTDNVEGKNMFKTISNMLSLELLLEPTFLLFAISNLLTSV 404

  Fly   686 GFNIPFVYSSARTT----IPVEYARMIGPIIGISNLVMRNILGILA--------------YKRRS 732
            |||.|..:.....|    .|::.::::. ..|:||.|.|.|.|::|              .:.|.
 Worm   405 GFNSPLYFLPLHATKIGLEPIQGSKVLS-AFGVSNTVGRIIFGVVADHKLPLPGGIGNDTARNRL 468

  Fly   733 W--TLGLCGCGLIFGGVSVLISAFYG-ENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKL 794
            |  .:.|..|||:    :|....|.| ..|..:..|:|||.    |.|..|..:|.|..|||.||
 Worm   469 WMYNISLTICGLL----TVFCYQFNGFIPLATYSALFGFSI----ASYICLTSVILVDLLGLDKL 525

  Fly   795 TNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIK 852
            |||||:..|..|:|...|..::|.|..:||||:.:|.|.|:.|:.||.:...:|...|
 Worm   526 TNAFGLLLLWQGVGTVFGPPVSGYLADMTGNYTLSFVFCGVNLLASGLMLFGIPFFQK 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	41/180 (23%)
		MFS	675..>839	CDD:119392	59/184 (32%)
mct-6	NP_510705.1	MFS_MCT_SLC16	23..579	CDD:340910	149/613 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820