Protein Alignment CG12866 and gem-1

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001379120.1
• Gene: gem-1 / 181458
• WormBaseID: WBGene00008214
• Length: 771
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 143/714 - (20%)
• Similarity: 262/714 - (36%)
• Gaps: 205/714 - (28%)

  Fly   300 DGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLD----VSISSVSFVASVQIGCYFTSGAF 360
            |||:||::::.|||...:.||..|..|::...|.:...    ||:.:.|...|:.:.....:|..
 Worm    68 DGGYGWLVVLASFLMHAVCDGASFCFGIVFVKIQEHFQCGRFVSMITASMFLSLPLIMSPVAGIV 132

  Fly   361 SAVLINRFGFRKVAIAGV-LCSAVSILASSWSVSLTMLIFFYSV---LACAGGITLSMIWASSQL 421
            |.:|    |.|...|.|. :|:...|:|...|     .|||:.:   |.|  |:.:|.|:.::.:
 Worm   133 SDIL----GCRMSIIIGASICTVSCIIAMFCS-----HIFFFMISFGLGC--GVGMSFIYNAAIV 186

  Fly   422 IVGYYFERYRPMANGFSCSGGGAGIVLF-TFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVE 485
            ||.||||:.|.:|..|:.||.|.|.|:: ..||..::.:..:.:.:|      ::::...|.|..
 Worm   187 IVTYYFEKRRGLATSFAVSGTGVGTVIYPILLNLSMIYLASFVSDIR------IILIFFAVMYFV 245

  Fly   486 VAPTQVGMYHLPGSSDTS--------------SDEYYGNFYVHDYLRQSAMTAKSRSILSTY--- 533
            :|.....:..:...||.:              .||...|....|...:.|::..:.:||:.:
 Worm   246 IAVIGFFIKDVEWESDKTDFKLRKFQKYIAKMDDEKENNTNPTDAFMRHAISLPNLNILNNHSGS 310

  Fly   534 -------------EPRP-KKKGCAKF-------------------------------CPSCSNCC 553
                         ..:| :.|..|.|                               .|..:...
 Worm   311 IQSICDAAKAERKSDKPTRSKSVALFDNKHQMSSIPEYSMLNTNLANLEHLDLELANSPCTTVRA 375

  Fly   554 WRRR---KKSQNADEQNLLIRPAPLERE----DLFYTGPA-----EYEKPHSKENVDGKEFLLMG 606
            .|||   |.|.:.|:.|      .||.|    :||.:...     |.....|:.:.||.......
 Worm   376 QRRRVISKVSMSVDQIN------ELEDEAFHINLFQSSTESESDDESSSDDSEMSNDGDSSSSEL 434

  Fly   607 SDKN-----TQQVNYGIKNI--------------------------------------------- 621
            |:||     |:.:|..::|:
 Worm   435 SEKNLDEPTTKLINKNLENVAFRATSSVPNSARMNRNSVAAGTSNMFGGRVIASNAIQSRHATNL 499

  Fly   622 ----RVDDEPDRISRVHRE-----------RRWSNENQK----KQNSCRNSRFM-LTVLKLFDYR 666
                ::...|..::|.:|:           ::|. |.:|    :...||...:: |:||.|:
 Worm   500 IAMGKIPSAPMLVARKNRKSMIGKPIQGFYKKWL-ETEKPIYQEVIHCRAYIYLALSVLCLY--- 560

  Fly   667 LLKQFEFKILVASAFLFPMGFNIPFV--YSSARTTIPVE--YARMIGPIIGISNLVMRNILGILA 727
                          |:    .::|:|  |..:..|:.:|  .|..|...|||||.:...:.|.||
 Worm   561 --------------FI----LDVPYVCFYEYSIDTLKMEESEANYIYYSIGISNFISVLLFGTLA 607

  Fly   728 YKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRG-LIYVKYLGL 791
            ...|.....:....::..|::::.|...  |.:....:.|..:.|.......|:. |:.:.:..:
 Worm   608 DWTRKHITTIYASSMVGVGITIMFSTRI--NSLVELVIVGVCFGVTITSNYVLQSILVTICFEDV 670

  Fly   792 SKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRN 855
            :....|:.:.::..|:.:.||..|...:...||.|:..|..:|:..:.|||...:....:..||
 Worm   671 NLFQVAYSLIAMIEGVASLIGPPIFALVREATGGYTVVFFISGIFALASGFFGFMFSYEMNKRN 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	49/184 (27%)
		MFS	675..>839	CDD:119392	34/168 (20%)
gem-1	NP_001379120.1	MFS	72..>254	CDD:421695	53/198 (27%)
		MFS	<543..727	CDD:421695	43/206 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820