back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12866 and Slc16a10

DIOPT Version :9

Sequence 1:	NP_001286425.1	Gene:	CG12866 / 36630	FlyBaseID:	FBgn0033955	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_620186.1	Gene:	Slc16a10 / 170566	RGDID:	69197	Length:	514	Species:	Rattus norvegicus

Alignment Length:	577	Identity:	122/577 - (21%)
Similarity:	202/577 - (35%)	Gaps:	180/577 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTI----GVLLPSI-----AQDLDVSISSVSFVASVQIGC 353
            ||:||:||::|    ||.:..:|.:|.|    |||..|:     |:|.|......::|.|:.:|.
  Rat    63 PPEGGWGWLVM----LAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGM 123

  Fly   354 YFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWAS 418
            .|......:|..:.||.|:.|:.|.....|.:::||:..|:..|.|.|.|:...|   .|..:..
  Rat   124 IFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACG---CSFAYQP 185

  Fly   419 SQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAY 483
            |.:|:|:||::...:.||...:|.....:|...|...|...:|....||      :|.:.|.|.:
  Rat   186 SLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLR------ILCIFMFVLF 244

  Fly   484 VEVAPTQVGMYH---LPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKF 545
            :      .|..:   :|.|.:..|::...:|:             ||..||.    |||......
  Rat   245 L------AGFTYRPLVPSSKEKESEDSRSSFF-------------SRRKLSP----PKKIFNFAL 286

  Fly   546 CPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLF-YTGPAEYEKPHSKE---NVDGKE--FLL 604
            ....:...|               ....||.   || |..|..:...|.||   :|:.||  |:.
  Rat   287 FKETAYAVW---------------AAGIPLA---LFGYFVPYVHLMNHVKERFKDVNNKEVLFMC 333

  Fly   605 MGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLK 669
            :|......::.:|    |:.|....:.:|:                      |.||..|
  Rat   334 IGVTSGVGRLLFG----RIADYLPGVKKVY----------------------LQVLSFF------ 366

  Fly   670 QFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWT 734
                                                     .||:::::
  Rat   367 -----------------------------------------FIGLTSMM---------------- 374

  Fly   735 LGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFG 799
            :.||.   :||.:..|.       ||...|...|...:||..:         :.:|....:.|.|
  Rat   375 IPLCS---VFGALIALC-------LIMGLFDGCFISIMAPIAF---------ELVGPQDASQAIG 420

  Fly   800 ITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNR 856
            .....|.:...:|..:||.|....|:|..||..||:...:.|.:..|:|.:...:.|
  Rat   421 FLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQR 477

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.