Protein Alignment CG12866 and SLC16A11

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001357478.1
• Gene: SLC16A11 / 162515
• HGNCID: 23093
• Length: 447
• Species: Homo sapiens
• Alignment Length: 585
• Identity: 109/585 - (18%)
• Similarity: 189/585 - (32%)
• Gaps: 223/585 - (38%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSA 362
            |||||:|||:...:|....:..||:.::|:..|.:|:..|.|....::::::.:.....:....:
Human     8 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGS 72

  Fly   363 VLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYF 427
            .|..|:|.|.|.:.|.:.:::..:.|:::   :.|:..|..|....|...::::|.:...:..||
Human    73 ALSTRWGARPVVMVGGVLASLGFVFSAFA---SDLLHLYLGLGLLAGFGWALVFAPALGTLSRYF 134

  Fly   428 ERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNML---------RTQAGLIMLILLMVVAY 483
            .|.|.:|.|.:.:|.||..:|.......|:...|||..|         .|..|.::|.|:
Human   135 SRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLV----- 194

  Fly   484 VEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPS 548
                        |||                                   :|
Human   195 ------------LPG-----------------------------------DP------------- 199

  Fly   549 CSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQ 613
                                   ||| .|..|...|
Human   200 -----------------------PAP-PRSPLAALG----------------------------- 211

  Fly   614 VNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVA 678
                                                          |.||..|     .|.|...
Human   212 ----------------------------------------------LSLFTRR-----AFSIFAL 225

  Fly   679 SAFLFPMGFNIPFVYSSARTTIPVEYARMIG--------PIIGISNLVMRNILGILAYKRRSWT- 734
            ...|...|:.:|:|:.:     |....|.:|        .:..:.:...|.:.|.||  .:.|.
Human   226 GTALVGGGYFVPYVHLA-----PHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLA--DQGWVP 283

  Fly   735 -------------LGLCGCGL--IFGGVSVLISAFYGENLIWFQFLYGFSY-AVAPAVYSTLRGL 783
                         |||...||  :.||     ...:|..|:.....||.|. :.||.|:..|.||
Human   284 LPRLLAVFGALTGLGLWVVGLVPVVGG-----EESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGL 343

  Fly   784 IYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLP 848
            :     |:..:..|.|:..:.|.:|..:|..::|.|...||:::|:|..:|..::...|:.:.||
Human   344 V-----GVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLP 403

  Fly   849  848
            Human   404  403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	39/184 (21%)
		MFS	675..>839	CDD:119392	44/188 (23%)
SLC16A11	NP_001357478.1	MFS	14..403	CDD:355786	102/577 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950