Protein Alignment CG12866 and SLC16A14

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 139/602 - (23%)
• Similarity: 227/602 - (37%)
• Gaps: 184/602 - (30%)

  Fly   300 DGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAVL 364
            |||:.|::::.||...::|.|....:|||.....::...|....::|:|:.:|.....|.|..:.
Human    29 DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLF 93

  Fly   365 INRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFER 429
            ||..|.|:.||.|.|.:::..:.|:::.::..|...:.|   |.|:...|.:..:.::||.||::
Human    94 INTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGV---AAGLGSGMAYLPAVVMVGRYFQK 155

  Fly   430 YRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMY 494
            .|.:|.|.|.:|.|.|..|.|.|..:|....||||.:..| |.:.|.|.:..|.:
Human   156 RRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQ-GAVSLNLCVCGALM---------- 209

  Fly   495 HLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKK 559
                                                     ||...|                |.
Human   210 -----------------------------------------RPLSPG----------------KN 217

  Fly   560 SQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKN---- 620
            ..:..|:::...||                  ||.|:|..     .|....|::.:.|:.|
Human   218 PNDPGEKDVRGLPA------------------HSTESVKS-----TGQQGRTEEKDGGLGNEETL 259

  Fly   621 --IRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDY---RLLKQFE-------- 672
              ::..:.||:..  ||           :|.|     .|.:||...:   |:.|.||
Human   260 CDLQAQECPDQAG--HR-----------KNMC-----ALRILKTVSWLTMRVRKGFEDWYSGYFG 306

  Fly   673 ----FKILVASAFLF-----PMGFNIPFVY----------SSARTTIPVEYARMIGPIIGISNLV 718
                |...:..||:|     ...|.|||::          |......|      :..||.|.::.
Human   307 TASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFP------LTSIIAIVHIF 365

  Fly   719 MRNILGILA----------YKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFS---Y 770
            .:.|||::|          :...::||.|.    ||  :..|:..:.|..:|.  .|.|||   :
Human   366 GKVILGVIADLPCISVWNVFLLANFTLVLS----IF--ILPLMHTYAGLAVIC--ALIGFSSGYF 422

  Fly   771 AVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGL 835
            ::.|.|...|        :|:..|.||:||...|.|:.|.:|...||.:..||..|..:|...||
Human   423 SLMPVVTEDL--------VGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGL 479

  Fly   836 CLIVSGFLKLLLPLLIK 852
             |.:.|.|.||:...|:
Human   480 -LYMIGILFLLIQPCIR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	51/175 (29%)
		MFS	675..>839	CDD:119392	50/191 (26%)
SLC16A14	NP_689740.2	2A0111	24..490	CDD:331689	137/595 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		12/79 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145554
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750