Protein Alignment CG12866 and SLC16A10

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_061063.2
• Gene: SLC16A10 / 117247
• HGNCID: 17027
• Length: 515
• Species: Homo sapiens
• Alignment Length: 577
• Identity: 119/577 - (20%)
• Similarity: 199/577 - (34%)
• Gaps: 180/577 - (31%)

  Fly   298 PPDGGFGWVIMVLSFLAQLIIDGLIFTI----GVLLPSI-----AQDLDVSISSVSFVASVQIGC 353
            ||:||:||::|    ||.:..:|.:|.|    |||..|:     ::|.|..:...::|.|:.:|.
Human    64 PPEGGWGWLVM----LAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGM 124

  Fly   354 YFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWAS 418
            .|......:|..:.||.||.|:.|.....|.:::||:..|:..|...|.::...|   .|..:..
Human   125 IFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACG---CSFAYQP 186

  Fly   419 SQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAY 483
            |.:|:|:||::...:.||...:|.....:|...|...|:..:|....||      :|.:.|.|.:
Human   187 SLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLR------VLCIFMFVLF 245

  Fly   484 VEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPS 548
            :      .|..:.|.::.|...|..|:        .|::.::.:     :.| |||.........
Human   246 L------AGFTYRPLATSTKDKESGGS--------GSSLFSRKK-----FSP-PKKIFNFAIFKV 290

  Fly   549 CSNCCWRRRKKSQNADEQNLLIRPAPLEREDLF-YTGPAEYEKPHSKENVD---GKEFLLM--GS 607
            .:...|               ....||.   || |..|..:...|..|...   .||.:||  |.
Human   291 TAYAVW---------------AVGIPLA---LFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGV 337

  Fly   608 DKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFE 672
            .....::.:|    |:.|....:.:|:                      |.||..|
Human   338 TSGVGRLLFG----RIADYVPGVKKVY----------------------LQVLSFF--------- 367

  Fly   673 FKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGL 737
                    |:..|...||                                              |
Human   368 --------FIGLMSMMIP----------------------------------------------L 378

  Fly   738 CGCGLIFG---GVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFG 799
            |.   |||   .|.:::..|.|          .|...:||..:         :.:|...::.|.|
Human   379 CS---IFGALIAVCLIMGLFDG----------CFISIMAPIAF---------ELVGAQDVSQAIG 421

  Fly   800 ITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNR 856
            .....|.:...:|..|||.|....|:|..||..||:..::.|.:...:|.:...:.|
Human   422 FLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQR 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	48/184 (26%)
		MFS	675..>839	CDD:119392	30/166 (18%)
SLC16A10	NP_061063.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		2A0113	67..487	CDD:273325	117/574 (20%)
		MFS	71..470	CDD:119392	112/560 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4122
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.700