Protein Alignment CG12866 and slc16a2

DIOPT Version :9

• Sequence 1: NP_001286425.1
• Gene: CG12866 / 36630
• FlyBaseID: FBgn0033955
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001245159.1
• Gene: slc16a2 / 100884148
• ZFINID: ZDB-GENE-120117-1
• Length: 526
• Species: Danio rerio
• Alignment Length: 674
• Identity: 136/674 - (20%)
• Similarity: 220/674 - (32%)
• Gaps: 248/674 - (36%)

  Fly   218 SEDSYVVPKETDQQESGLSFNVTTVQLADT-------ASPESFSEYDGNRTRKQSFDMESKNSKE 275
            :|:|....:|.::||..|:...:||||..|       |:|.
Zfish    21 AEESSSPAEEFEEQERKLAPEDSTVQLIHTGCTDKRPATPP------------------------ 61

  Fly   276 SFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIA-----QD 335
                   |...|.|.|      ||:||||||::..:......|.|:..:.|:|...:.     |.
Zfish    62 -------GAHPGQGFV------PPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQP 113

  Fly   336 LDVSISSVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFF 400
            ...|...|::|.::.:|..|......::..:.||.||.|:.|...:.:.:|.||::.:|.:..|.
Zfish   114 DQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFT 178

  Fly   401 YSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNM 465
            |.:|...|.   |..:..|.:|:|:||.:...:|||...:|.....:....|...:|..:|....
Zfish   179 YGILFGCGS---SFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRT 240

  Fly   466 LRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSIL 530
            .:..:..:::..|:.:|:..:.|:  ||..:||.:                |.....|.:|.|
Zfish   241 FQILSIFMLVQALLALAFKPLLPS--GMCPMPGMA----------------LDGGPSTPESAS-- 285

  Fly   531 STYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKE 595
                  ..:||.||.
Zfish   286 ------RWQKGLAKI-------------------------------------------------- 294

  Fly   596 NVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVL 660
                                                     ||:               |.:.|.
Zfish   295 -----------------------------------------RRY---------------FNVRVF 303

  Fly   661 KLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGI 725
            .:..||:     :...||:|.|   |:.:|:|:                    :.|.|...
Zfish   304 SILTYRI-----WAFGVATAVL---GYFVPYVH--------------------LLNFVKEQ---- 336

  Fly   726 LAYKRRSWTLGLC-----GCG-LIFGGVSVLISAFYGENLIWFQ----FLYGFSYAVAP--AVYS 778
            ....:|.|.|.:|     |.| |:||.:..||.   |...|:.|    .|.|....:.|  ||:.
Zfish   337 FGDTQREWLLLVCIGASSGVGRLLFGKIGDLIP---GVKKIYMQVASFILLGVMSMMIPQCAVFE 398

  Fly   779 ------TLRGL-----------IYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNY 826
                  .|.||           |..:.:|..:.:.|.|.....|.:....|..|||.|....|||
Zfish   399 GLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNY 463

  Fly   827 SAAFCFAGLCLIVSGFLKLLLPLL 850
            ..||..||:..||.|.:...:||:
Zfish   464 HVAFYLAGVPPIVGGIVMFFVPLV 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12866	NP_001286425.1	MFS	308..>484	CDD:119392	39/180 (22%)
		MFS	675..>839	CDD:119392	48/192 (25%)
slc16a2	NP_001245159.1	2A0113	57..496	CDD:273325	125/638 (20%)
		MFS	78..485	CDD:119392	111/576 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010